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Asset Acquisition - Narrative (Details) - USD ($) $ / shares in Units, $ in Thousands | Jun. 22, 2023 | May 31, 2023
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Asset Acquisition [Line Items] |  |
Asset acquisition, contingent consideration, liability, current | $ 100 |
Cost to acquire asset | 113,200 |
Spyre Therapeutics, Inc. |  |
Asset Acquisition [Line Items] |  |
Cost to acquire asset | $ 113,176 |
Asset acquisition consideration transferred issuable shares of common stock on an as-converted basis | 14,595,480 |
Series A Non Voting Convertible Preferred Stock | Spyre Therapeutics, Inc. |  |
Asset Acquisition [Line Items] |  |
Shares transferred as equity interest in asset acquisition (in shares) | 364,887 |
Shares issued, price per share (in dollars per share) | $ 291.08 |
Common Stock | Spyre Therapeutics, Inc. |  |
Asset Acquisition [Line Items] |  |
Shares transferred as equity interest in asset acquisition (in shares) | 517,809 |
Shares issued, price per share (in dollars per share) | $ 7.277 |
Parapyre Option Obligation |  |
Asset Acquisition [Line Items] |  |
Percentage of annual equity grant of options | 1.00% | 1.00%
Spyre 2023 Equity Incentive Plan | Spyre Therapeutics, Inc. |  |
Asset Acquisition [Line Items] |  |
Number of outstanding and unexercised stock options to purchase (in shares) | 2,734 |

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