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Subsequent Events - Additional Information (Details) - $ / shares | Sep. 29, 2023 | Sep. 08, 2023 | Jul. 07, 2023 | Jun. 22, 2023 | Dec. 31, 2023 | Dec. 31, 2022
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Subsequent Event [Line Items] |  |  |  |  |  |
Common stock, par value |  |  |  |  | $ 0.0001 | $ 0.0001
Stockholders' equity, reverse stock split |  | 1-for-25 |  |  |  |
Spyre Therapeutics, Inc. | Common Stock |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Number of shares transferred as equity interest in asset acquisition |  |  |  | 517,809 |  |
Spyre Therapeutics, Inc. | Series A Non Voting Convertible Preferred Stock |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Number of shares transferred as equity interest in asset acquisition |  |  |  | 364,887 |  |
Subsequent Event |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Common stock, par value |  | $ 0.0001 |  |  |  |
Stockholders' equity, reverse stock split |  | 1-for-25 |  |  |  |
Subsequent Event | Parapyre Option Obligation |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Share-based payment award, term | 10 years |  |  |  |  |
Subsequent Event | Maximum |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Reduction in the total number of authorized shares |  | 500,000,000 |  |  |  |
Subsequent Event | Minimum |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Reduction in the total number of authorized shares |  | 20,000,000 |  |  |  |
Subsequent Event | Spyre Therapeutics, Inc. | Common Stock |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Number of shares transferred as equity interest in asset acquisition |  |  | 517,809 |  |  |
Subsequent Event | Spyre Therapeutics, Inc. | Series A Non Voting Convertible Preferred Stock |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Number of shares transferred as equity interest in asset acquisition |  |  | 364,887 |  |  |

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- Definition Asset acquisition consideration transferred equity interest issued and issuable, shares. + References No definition available. + Details
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- Definition Face amount or stated value per share of common stock. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 210 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(29)) -Publisher FASB -URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1 + Details
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- Definition Period from grant date that an equity-based award expires, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. + References Reference 1: http://www.xbrl.org/2003/role/exampleRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (a)(2) -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
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- Definition Reduction in the number of shares during the period as a result of a reverse stock split. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -SubTopic 10 -Topic 505 -Publisher FASB -URI https://asc.fasb.org//1943274/2147481112/505-10-50-2 + Details
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- Definition Description of the reverse stock split arrangement. Also provide the retroactive effect given by the reverse split that occurs after the balance sheet date but before the release of financial statements. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 4 -Subparagraph (SAB Topic 4.C) -Publisher FASB -URI https://asc.fasb.org//1943274/2147480008/505-10-S99-4 + Details
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- Definition Detail information of subsequent event by type. User is expected to use existing line items from elsewhere in the taxonomy as the primary line items for this disclosure, which is further associated with dimension and member elements pertaining to a subsequent event. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 830 -SubTopic 30 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Publisher FASB -URI https://asc.fasb.org//1943274/2147481674/830-30-50-2 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 855 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Publisher FASB -URI https://asc.fasb.org//1943274/2147483399/855-10-50-2 + Details
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