XML 65 R40.htm IDEA: XBRL DOCUMENT
v3.25.1

Licensing Agreements (Details) - Related Party - USD ($) |  |  | 3 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
Oct. 11, 2024 | May 14, 2024 | Mar. 31, 2025 | Mar. 31, 2024 | Dec. 31, 2024
Paragon Agreement |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Campaign timeline, minimum term |  |  | 5 years |  |
Royalty step-down percentage |  |  | 33.00% |  |
Royalty term expiration period |  |  | 12 years |  |
Termination notice period |  |  | 60 days |  |
Sublicensing fee |  |  | $ 0 | $ 0 |
Milestone expense recognized |  |  | 2,500,000 | 0 |
Milestone payments |  |  | 0 | 0 |
Milestone payments, outstanding and payable |  |  | 2,500,000 |  | $ 0
Payment for sublicensing fee |  |  | 500,000 | $ 0 |
SPY001 License Agreement | Maximum |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Contingent obligation based on milestones |  | $ 22,000,000.0 |  |  |
SPY002 License Agreement |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
First milestone payment |  | 3,000,000.0 |  |  |
SPY002 License Agreement | Maximum |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Contingent obligation based on milestones |  | $ 22,000,000.0 |  |  |
Sublicensing fee |  |  | 20,000,000 |  |
SPY003 License Agreement |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
First milestone payment | $ 3,000,000.0 |  |  |  |
SPY003 License Agreement | Maximum |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Contingent obligation based on milestones | $ 22,000,000.0 |  |  |  |
License Agreement |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Sublicensing fee, outstanding and payable |  |  | $ 0 |  | $ 500,000

X
- Definition Amount to be paid under agreement. + References No definition available. + Details
Name: | syre_AmountToBePaidUnderAgreement
Namespace Prefix: | syre_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

X
- Definition Campaign Timeline, Minimum Term + References No definition available. + Details
Name: | syre_CampaignTimelineMinimumTerm
Namespace Prefix: | syre_
Data Type: | xbrli:durationItemType
Balance Type: | na
Period Type: | duration

X
- Definition License Agreement, Milestone Expense, Amount Recognized + References No definition available. + Details
Name: | syre_LicenseAgreementMilestoneExpenseAmountRecognized
Namespace Prefix: | syre_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition License Agreement, Milestone Payments + References No definition available. + Details
Name: | syre_LicenseAgreementMilestonePayments
Namespace Prefix: | syre_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

X
- Definition License Agreement, Milestone Payments Outstanding and Payable + References No definition available. + Details
Name: | syre_LicenseAgreementMilestonePaymentsOutstandingAndPayable
Namespace Prefix: | syre_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

X
- Definition Payment For Sublicensing Fee + References No definition available. + Details
Name: | syre_PaymentForSublicensingFee
Namespace Prefix: | syre_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

X
- Definition Payment of milestone. + References No definition available. + Details
Name: | syre_PaymentOfMilestone
Namespace Prefix: | syre_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

X
- Definition Royalty Step-Down, Percent + References No definition available. + Details
Name: | syre_RoyaltyStepDownPercent
Namespace Prefix: | syre_
Data Type: | dtr-types:percentItemType
Balance Type: | na
Period Type: | instant

X
- Definition Royalty Term, Expiration Period + References No definition available. + Details
Name: | syre_RoyaltyTermExpirationPeriod
Namespace Prefix: | syre_
Data Type: | xbrli:durationItemType
Balance Type: | na
Period Type: | duration

X
- Definition Sublicensing Fee + References No definition available. + Details
Name: | syre_SublicensingFee
Namespace Prefix: | syre_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition Sublicensing Fee, Outstanding And Payable + References No definition available. + Details
Name: | syre_SublicensingFeeOutstandingAndPayable
Namespace Prefix: | syre_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

X
- Definition Termination Notice Period + References No definition available. + Details
Name: | syre_TerminationNoticePeriod
Namespace Prefix: | syre_
Data Type: | xbrli:durationItemType
Balance Type: | na
Period Type: | duration

X
- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 310 -SubTopic 10 -Name Accounting Standards Codification -Section 45 -Paragraph 13 -Publisher FASB -URI https://asc.fasb.org/1943274/2147481990/310-10-45-13 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 946 -SubTopic 220 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.6-07(2)(c)(2)(i)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479134/946-220-S99-1 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Topic 946 -SubTopic 220 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.6-07(2)(c)(2)(ii)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479134/946-220-S99-1 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Topic 946 -SubTopic 220 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.6-07(2)(g)(3)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479134/946-220-S99-1 + Details
Name: | us-gaap_RelatedPartyTransactionLineItems
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- Details
Name: | us-gaap_RelatedPartyTransactionsByRelatedPartyAxis=us-gaap_RelatedPartyMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_RelatedPartyTransactionAxis=syre_ParagonAgreementMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_RelatedPartyTransactionAxis=syre_Spy001LicenseAgreementMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | srt_RangeAxis=srt_MaximumMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_RelatedPartyTransactionAxis=syre_SPY002LicenseAgreementMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_RelatedPartyTransactionAxis=syre_SPY003LicenseAgreementMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_RelatedPartyTransactionAxis=syre_ParagonAgreementLicenseMilestonePaymentsMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |