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Related Party Transactions - Narrative (Details) $ / shares in Units, $ in Thousands |  | 3 Months Ended | 9 Months Ended |  |
--- | --- | --- | --- | --- | ---
Nov. 22, 2023 $ / shares shares | Sep. 30, 2025 USD ($) seat shares | Sep. 30, 2024 USD ($) shares | Sep. 30, 2025 USD ($) seat shares | Sep. 30, 2024 USD ($) shares | Apr. 01, 2024 | Mar. 31, 2024
Related Party Transaction [Line Items] |  |  |  |  |  |  |
Stock-based compensation expense |  |  | $ 13,100 | $ 27,803 | $ 35,617 |  |
Options granted to purchase (in shares) | shares |  | 213,900 | 425,500 | 2,539,617 | 1,857,853 |  |
Stock-based compensation expense |  | $ 9,566 | $ 13,100 | $ 27,803 | $ 35,617 |  |
Parapyre Option Obligation |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |
Stock-based compensation expense |  |  | 6,100 |  | 13,000 |  |
Related Party |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |
Development cost reduction (as percent) |  |  |  |  |  | 50.00% |
Development cost reimbursement (as percent) |  |  |  |  |  |  | 50.00%
Stock-based compensation expense |  | 300 | 6,400 | 800 | 13,800 |  |
Paragon Agreement | Related Party |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |
Amount of related party transaction |  | $ 0 | 1,200 | $ 200 | 30,700 |  |
Reduction in research and development expense |  |  |  |  | 5,900 |  |
Common stock, shares outstanding, percentage available to purchase on a diluted basis |  | 1.00% |  | 1.00% |  |  |
Appoint Of Board Members |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |
Number of board seats held by related party | seat |  | 2 |  | 2 |  |  |
Subsequent to Asset Acquisition | Related Party |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |
Amount of related party transaction |  | $ 0 | 7,400 | $ 100 | 28,300 |  |
Consulting Agreement | Related Party |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |
Options granted to purchase (in shares) | shares | 477,000 |  |  |  |  |  |
Exercise price (in dollars per share) | $ / shares | $ 10.39 |  |  |  |  |  |
Vest period grant date (in years) | 36 months |  |  |  |  |  |
Stock-based compensation expense |  | $ 300 | $ 300 | $ 800 | $ 800 |  |
Consulting Agreement | Related Party | Share-Based Payment Arrangement, Tranche One |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |
Vesting percentage | 25.00% |  |  |  |  |  |
Vest period grant date (in years) | 1 year |  |  |  |  |  |
Paragon Therapeutics Inc | Maximum | Paragon Agreement | Related Party |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |
Percentage of ownership by noncontrolling owner |  | 5.00% |  | 5.00% |  |  |
Fairmount Funds Management LLC | Minimum | Paragon Agreement | Related Party |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |
Percentage of ownership by noncontrolling owner |  | 5.00% |  | 5.00% |  |  |
Percentage of ownership held in third party |  | 5.00% |  | 5.00% |  |  |

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