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Commitments (Detail) - USD ($) | 3 Months Ended
--- | ---
Mar. 31, 2018 | Mar. 31, 2017
Contractual Obligation [Line Items] |  |
Capital lease obligation amount | $ 3,355,000 | $ 1,898,000
Laboratory And Computer Equipment |  |
Contractual Obligation [Line Items] |  |
Capital lease obligation amount | $ 3,400,000 |
Lease term | 36 months |
Capital leases buy out amount | $ 1 |
Minimum | Laboratory And Computer Equipment |  |
Contractual Obligation [Line Items] |  |
Capital lease interest rate | 4.60% |
Maximum | Laboratory And Computer Equipment |  |
Contractual Obligation [Line Items] |  |
Capital lease interest rate | 5.60% |

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