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Investment in Non-Consolidated Affiliate (Details) $ in Thousands |  |  |  | 3 Months Ended | 12 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | ---
Sep. 30, 2021 USD ($) | Jun. 18, 2021 USD ($) | May 22, 2020 USD ($) | Mar. 31, 2021 USD ($) | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | Dec. 31, 2019 USD ($) | May 22, 2021 USD ($) | Jan. 31, 2021 USD ($) | May 31, 2020 USD ($)
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Carrying amount of investment in non-consolidated affiliate |  |  |  |  | $ 1,869,778 | $ 988,331 |  |  |  |
Investment in non-consolidated affiliate |  |  |  |  | 0 | 29,555 |  |  |  |
Gain on settlement under line of credit |  |  |  |  | 4,700 |  |  |  |  |
Gain on investment in and loan receivable from non-consolidated affiliate, net |  |  |  |  | 109,260 | 3,955 | $ 0 |  |  |
Inivata |  |  |  |  |  |  |  |  |  |
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Fair value of previously-held equity interest | $ 64,900 | $ 64,906 |  |  |  |  |  |  |  |
Fair value of Purchase Option | $ 74,300 | 74,300 |  |  |  |  |  |  |  |
Unrealized gain on investment in non-consolidated affiliate, net |  |  |  |  | 104,600 |  |  |  |  |
Measurement period adjustments, net assets acquired |  | 17,750 |  |  | 17,800 |  |  |  |  |
Gain on investment in and loan receivable from non-consolidated affiliate, net |  |  |  |  | $ 109,300 | 4,000 |  |  |  |
Variable Interest Entity, Not Primary Beneficiary |  |  |  |  |  |  |  |  |  |
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Carrying amount of investment in non-consolidated affiliate |  |  |  |  |  | 29,600 |  |  |  |
Unrealized gain on remeasurement |  |  |  |  |  | 4,000 |  |  |  |
Preference Shares | Variable Interest Entity, Not Primary Beneficiary |  |  |  |  |  |  |  |  |  |
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Carrying amount of investment in non-consolidated affiliate |  |  |  |  |  | 25,000 |  |  |  |
Investment in non-consolidated affiliate |  |  |  |  |  |  |  |  | $ 30,000 |
Preference Shares | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Risk Free Interest Rate |  |  |  |  |  |  |  |  |  |
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Purchase option, measurement input (as a percent) |  |  |  |  | 0.0017 |  |  |  |  |
Preference Shares | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Price Volatility |  |  |  |  |  |  |  |  |  |
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Purchase option, measurement input (as a percent) |  |  |  |  | 0.840 |  |  |  |  |
Preference Shares | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Expected Dividend Rate |  |  |  |  |  |  |  |  |  |
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Purchase option, measurement input (as a percent) |  |  |  |  | 0.000 |  |  |  |  |
Purchase Option | Variable Interest Entity, Not Primary Beneficiary |  |  |  |  |  |  |  |  |  |
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Carrying amount of investment in non-consolidated affiliate |  |  |  |  |  | $ 4,600 |  |  |  |
Purchase Option | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Risk Free Interest Rate |  |  |  |  |  |  |  |  |  |
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Purchase option, measurement input (as a percent) |  |  |  |  | 0.0017 | 0.0017 |  |  |  |
Purchase Option | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Price Volatility |  |  |  |  |  |  |  |  |  |
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Purchase option, measurement input (as a percent) |  |  |  |  | 0.840 | 0.840 |  |  |  |
Purchase Option | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Expected Dividend Rate |  |  |  |  |  |  |  |  |  |
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Purchase option, measurement input (as a percent) |  |  |  |  | 0.000 | 0.000 |  |  |  |
Affiliated Entity |  |  |  |  |  |  |  |  |  |
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Net unrealized loss from remeasurement of investment |  |  |  | $ 5,000 |  |  |  |  |  |
Amount outstanding under line of credit |  | 10,300 |  |  |  |  |  |  |  |
Affiliated Entity | Line of Credit |  |  |  |  |  |  |  |  |  |
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Line of credit facility maximum borrowing capacity |  |  | $ 15,000 |  |  |  |  | $ 15,000 |  |
Interest rate per annum (as a percent) |  |  |  |  | 0.00% |  |  |  |  |
Imputed interest rate (as a percent) |  |  |  |  |  |  |  |  | 8.33% |
Loan with imputed interest, discount) |  |  |  |  |  |  |  |  | $ 5,000 |
Additional investment in non-consolidated affiliate |  |  |  |  |  |  |  |  | 5,000 |
Present value of loan receivable with imputed interest |  |  |  |  |  |  |  |  | $ 10,000 |
Amount outstanding under line of credit |  | 10,300 |  |  |  |  |  |  |  |
Affiliated Entity | Variable Interest Entity, Not Primary Beneficiary |  |  |  |  |  |  |  |  |  |
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Investment in minority interest |  | 29,600 | 25,000 | 29,600 |  |  |  |  |  | $ 25,000
Transaction costs |  |  | 600 |  |  |  |  |  |  |
Affiliated Entity | Variable Interest Entity, Not Primary Beneficiary | Line of Credit |  |  |  |  |  |  |  |  |  |
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Interest income from loan receivable |  |  |  |  | $ 400 |  |  |  |  |
Affiliated Entity | Preference Shares | Variable Interest Entity, Not Primary Beneficiary |  |  |  |  |  |  |  |  |  |
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Investment in minority interest |  | 25,000 | 19,600 | 25,000 |  |  |  |  |  |
Affiliated Entity | Purchase Option | Variable Interest Entity, Not Primary Beneficiary |  |  |  |  |  |  |  |  |  |
Schedule of Equity Method Investments [Line Items] |  |  |  |  |  |  |  |  |  |
Investment in minority interest |  | $ 4,600 | $ 6,000 | $ 4,600 |  |  |  |  |  |

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- Definition Fair value at acquisition-date of the equity interest in the acquiree held by the acquirer, immediately before the acquisition date for businesses combined in stages. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (g)(1) -URI http://asc.fasb.org/extlink&oid=79982066&loc=d3e1392-128463 + Details
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- Definition In a business combination achieved in stages, this element represents the amount of gain recognized by the entity as a result of remeasuring to fair value the equity interest in the acquiree it held before the business combination. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (g)(2) -URI http://asc.fasb.org/extlink&oid=79982066&loc=d3e1392-128463 + Details
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- Definition The aggregate interest and fee income generated by: (1) loans the Entity has positive intent and ability to hold for the foreseeable future, or until maturity or payoff, including commercial and consumer loans, whether domestic or foreign, which may consist of: (a) industrial and agricultural; (b) real estate; and (c) real estate construction loans; (d) trade financing; (e) lease financing; (f) home equity lines-of-credit; (g) automobile and other vehicle loans; and (h) credit card and other revolving-type loans and (2) loans and leases held-for-sale which may include mortgage loans, direct financing, and sales-type leases. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 942 -SubTopic 220 -Section S99 -Paragraph 1 -Subparagraph (SX 210.9-04.1) -URI http://asc.fasb.org/extlink&oid=120399700&loc=SL114874048-224260 + Details
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