    <SEC-DOCUMENT>0001104659-20-103458-index.html : 20200909
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    ACCESSION NUMBER:		0001104659-20-103458
    CONFORMED SUBMISSION TYPE:	S-1
    PUBLIC DOCUMENT COUNT:		41
    FILED AS OF DATE:		20200909
    DATE AS OF CHANGE:		20200909

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Immunome Inc.
    		CENTRAL INDEX KEY:			0001472012
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				770694340
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		S-1
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-248687
    		FILM NUMBER:		201166712

    	BUSINESS ADDRESS:
    		STREET 1:		665 STOCKTON DRIVE
    		STREET 2:		SUITE 300
    		CITY:			EXTON
    		STATE:			PA
    		ZIP:			19341
    		BUSINESS PHONE:		610-321-3700

    	MAIL ADDRESS:
    		STREET 1:		665 STOCKTON DRIVE
    		STREET 2:		SUITE 300
    		CITY:			EXTON
    		STATE:			PA
    		ZIP:			19341
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    <FILENAME>tm2025599-3_s1.htm
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    <TEXT>
    Document 1 - file: tm2025599-3_s1.htm

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    <TYPE>EX-1.1
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    <FILENAME>tm2025599d4_ex1-1.htm
    <DESCRIPTION>EXHIBIT 1.1
    <TEXT>
    Document 2 - file: tm2025599d4_ex1-1.htm

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    <SEQUENCE>3
    <FILENAME>tm2025599d4_ex3-1.htm
    <DESCRIPTION>EXHIBIT 3.1
    <TEXT>
    Document 3 - file: tm2025599d4_ex3-1.htm

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    <DOCUMENT>
    <TYPE>EX-3.2
    <SEQUENCE>4
    <FILENAME>tm2025599d4_ex3-2.htm
    <DESCRIPTION>EXHIBIT 3.2
    <TEXT>
    Document 4 - file: tm2025599d4_ex3-2.htm

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    <TYPE>EX-3.3
    <SEQUENCE>5
    <FILENAME>tm2025599d4_ex3-3.htm
    <DESCRIPTION>EXHIBIT 3.3
    <TEXT>
    Document 5 - file: tm2025599d4_ex3-3.htm

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    <SEQUENCE>6
    <FILENAME>tm2025599d4_ex3-4.htm
    <DESCRIPTION>EXHIBIT 3.4
    <TEXT>
    Document 6 - file: tm2025599d4_ex3-4.htm

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    <FILENAME>tm2025599d2_ex4-1.htm
    <DESCRIPTION>EXHIBIT 4.1
    <TEXT>
    Document 7 - file: tm2025599d2_ex4-1.htm

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    <DESCRIPTION>EXHIBIT 4.3
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    Document 8 - file: tm2025599d2_ex4-3.htm

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    <FILENAME>tm2025599d4_ex10-1.htm
    <DESCRIPTION>EXHIBIT 10.1
    <TEXT>
    Document 9 - file: tm2025599d4_ex10-1.htm

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    <SEQUENCE>10
    <FILENAME>tm2025599d4_ex10-2.htm
    <DESCRIPTION>EXHIBIT 10.2
    <TEXT>
    Document 10 - file: tm2025599d4_ex10-2.htm

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    <SEQUENCE>11
    <FILENAME>tm2025599d4_ex10-3.htm
    <DESCRIPTION>EXHIBIT 10.3
    <TEXT>
    Document 11 - file: tm2025599d4_ex10-3.htm

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    <SEQUENCE>12
    <FILENAME>tm2025599d4_ex10-4.htm
    <DESCRIPTION>EXHIBIT 10.4
    <TEXT>
    Document 12 - file: tm2025599d4_ex10-4.htm

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    <SEQUENCE>13
    <FILENAME>tm2025599d4_ex10-5.htm
    <DESCRIPTION>EXHIBIT 10.5
    <TEXT>
    Document 13 - file: tm2025599d4_ex10-5.htm

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    <SEQUENCE>14
    <FILENAME>tm2025599d4_ex10-9.htm
    <DESCRIPTION>EXHIBIT 10.9
    <TEXT>
    Document 14 - file: tm2025599d4_ex10-9.htm

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    <SEQUENCE>15
    <FILENAME>tm2025599d4_ex10-10.htm
    <DESCRIPTION>EXHIBIT 10.10
    <TEXT>
    Document 15 - file: tm2025599d4_ex10-10.htm

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    <SEQUENCE>16
    <FILENAME>tm2025599d4_ex10-11.htm
    <DESCRIPTION>EXHIBIT 10.11
    <TEXT>
    Document 16 - file: tm2025599d4_ex10-11.htm

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    <SEQUENCE>17
    <FILENAME>tm2025599d4_ex10-12.htm
    <DESCRIPTION>EXHIBIT 10.12
    <TEXT>
    Document 17 - file: tm2025599d4_ex10-12.htm

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    <SEQUENCE>18
    <FILENAME>tm2025599d4_ex10-13.htm
    <DESCRIPTION>EXHIBIT 10.13
    <TEXT>
    Document 18 - file: tm2025599d4_ex10-13.htm

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    <SEQUENCE>19
    <FILENAME>tm2025599d4_ex10-14.htm
    <DESCRIPTION>EXHIBIT 10.14
    <TEXT>
    Document 19 - file: tm2025599d4_ex10-14.htm

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    <SEQUENCE>20
    <FILENAME>tm2025599d4_ex10-15.htm
    <DESCRIPTION>EXHIBIT 10.15
    <TEXT>
    Document 20 - file: tm2025599d4_ex10-15.htm

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    <SEQUENCE>21
    <FILENAME>tm2025599d4_ex10-16.htm
    <DESCRIPTION>EXHIBIT 10.16
    <TEXT>
    Document 21 - file: tm2025599d4_ex10-16.htm

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    <TYPE>EX-10.17
    <SEQUENCE>22
    <FILENAME>tm2025599d4_ex10-17.htm
    <DESCRIPTION>EXHIBIT 10.17
    <TEXT>
    Document 22 - file: tm2025599d4_ex10-17.htm

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    <TYPE>EX-10.18
    <SEQUENCE>23
    <FILENAME>tm2025599d4_ex10-18.htm
    <DESCRIPTION>EXHIBIT 10.18
    <TEXT>
    Document 23 - file: tm2025599d4_ex10-18.htm

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    <TYPE>EX-10.19
    <SEQUENCE>24
    <FILENAME>tm2025599d4_ex10-19.htm
    <DESCRIPTION>EXHIBIT 10.19
    <TEXT>
    Document 24 - file: tm2025599d4_ex10-19.htm

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    <TYPE>EX-10.20
    <SEQUENCE>25
    <FILENAME>tm2025599d4_ex10-20.htm
    <DESCRIPTION>EXHIBIT 10.20
    <TEXT>
    Document 25 - file: tm2025599d4_ex10-20.htm

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    <TYPE>EX-23.1
    <SEQUENCE>26
    <FILENAME>tm2025599d4_ex23-1.htm
    <DESCRIPTION>EXHIBIT 23.1
    <TEXT>
    Document 26 - file: tm2025599d4_ex23-1.htm

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    <TYPE>GRAPHIC
    <SEQUENCE>27
    <FILENAME>lg_immunome-4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 27 - file: lg_immunome-4clr.jpg

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    <FILENAME>tm2025599d1-bc_signal4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 28 - file: tm2025599d1-bc_signal4clr.jpg

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    <FILENAME>tm2025599d1-ph_donors4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 29 - file: tm2025599d1-ph_donors4clr.jpg

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    <TYPE>GRAPHIC
    <SEQUENCE>30
    <FILENAME>tm2025599d1-ph_engine4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 30 - file: tm2025599d1-ph_engine4c.jpg

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    <TYPE>GRAPHIC
    <SEQUENCE>31
    <FILENAME>tm2025599d1-ph_response4clr.jpg
    <DESCRIPTION>GRAPHIC
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    Document 31 - file: tm2025599d1-ph_response4clr.jpg

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    <TYPE>GRAPHIC
    <SEQUENCE>32
    <FILENAME>tm2025599d1-ph_target4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 32 - file: tm2025599d1-ph_target4clr.jpg

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    <FILENAME>tm2025599d1-ph_tumorbw.jpg
    <DESCRIPTION>GRAPHIC
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    Document 33 - file: tm2025599d1-ph_tumorbw.jpg

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    <SEQUENCE>34
    <FILENAME>tm2025599d1-ph_viral4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 34 - file: tm2025599d1-ph_viral4clr.jpg

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    <DESCRIPTION>GRAPHIC
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    Document 35 - file: tm2025599d3-bc_screenbw.jpg

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    <TYPE>GRAPHIC
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    <FILENAME>tm2025599d3-lc_figure134c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 36 - file: tm2025599d3-lc_figure134c.jpg

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    <SEQUENCE>37
    <FILENAME>tm2025599d3-lc_figure54clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 37 - file: tm2025599d3-lc_figure54clr.jpg

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    <SEQUENCE>38
    <FILENAME>tm2025599d3-ph_figure24clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 38 - file: tm2025599d3-ph_figure24clr.jpg

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    Document 39 - file: tm2025599d3-ph_figure34clr.jpg

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    <TEXT>
    Document 40 - file: tm2025599d3-ph_figure74clr.jpg

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    <FILENAME>tm2025599d4_ex10-9img001.jpg
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    Document 41 - file: tm2025599d4_ex10-9img001.jpg

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