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Investments in Marketable Securities and Fair Value Measurements (Details) - USD ($) $ in Thousands | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019
--- | --- | --- | ---
Debt Securities, Available-for-sale [Line Items] |  |  |
Cash and cash equivalents | $ 213,082 | $ 41,092 | $ 22,646
Gross unrealized gain | 0 | 5 |
Gross unrealized loss | (799) | (11) |
Restricted cash | 5,358 | 5,196 | $ 5,816
Available-for-sale debt securities, amortized cost | 339,788 | 135,823 |
Available-for-sale debt securities fair value | 338,989 | 135,817 |
U.S. treasury and agency securities | Level 2 |  |  |
Debt Securities, Available-for-sale [Line Items] |  |  |
Amortized cost | 269,393 | 89,342 |
Gross unrealized gain | 0 | 5 |
Gross unrealized loss | (745) | (5) |
Fair Value | 268,648 | 89,342 |
Commercial paper | Level 2 |  |  |
Debt Securities, Available-for-sale [Line Items] |  |  |
Amortized cost | 27,187 | 2,848 |
Gross unrealized gain | 0 | 0 |
Gross unrealized loss | (7) | 0 |
Fair Value | 27,180 | 2,848 |
Debt securities | Level 2 |  |  |
Debt Securities, Available-for-sale [Line Items] |  |  |
Amortized cost | 33,366 | 17,774 |
Gross unrealized gain | 0 | 0 |
Gross unrealized loss | (47) | (6) |
Fair Value | 33,319 | 17,768 |
Certificates of deposit | Level 2 |  |  |
Debt Securities, Available-for-sale [Line Items] |  |  |
Amortized cost | 5,000 | 673 |
Gross unrealized gain | 0 | 0 |
Gross unrealized loss | 0 | 0 |
Fair Value | 5,000 | 673 |
Restricted cash | 335 |  |
Money market funds | Level 1 |  |  |
Debt Securities, Available-for-sale [Line Items] |  |  |
Cash and cash equivalents | 2,357 | 24,036 |
Commercial paper | Level 2 |  |  |
Debt Securities, Available-for-sale [Line Items] |  |  |
Cash and cash equivalents | 2,150 | 1,150 |
Cash and Cash Equivalents |  |  |
Debt Securities, Available-for-sale [Line Items] |  |  |
Cash and cash equivalents | 4,507 | 25,186 |
Marketable Securities |  |  |
Debt Securities, Available-for-sale [Line Items] |  |  |
Amortized cost | 334,946 | 110,637 |
Gross unrealized gain | 0 | 5 |
Gross unrealized loss | (799) | (11) |
Fair Value | $ 334,147 | $ 110,631 |

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