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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0000950146-00-000162.txt : 20000223
<SEC-HEADER>0000950146-00-000162.hdr.sgml : 20000223
ACCESSION NUMBER:		0000950146-00-000162
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20000222

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			LJL BIOSYSTEMS INC
		CENTRAL INDEX KEY:			0001042162
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				770360183
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		
		SEC FILE NUMBER:	005-53865
		FILM NUMBER:		550016

	BUSINESS ADDRESS:	
		STREET 1:		405 TASMAN DR
		CITY:			SUNNYVALE
		STATE:			CA
		ZIP:			94089
		BUSINESS PHONE:		4085418787

	MAIL ADDRESS:	
		STREET 1:		C/O LJ BIOSYSTEMS INC
		STREET 2:		405 TASMAN DRIVE
		CITY:			SUNNYVALE
		STATE:			CA
		ZIP:			94089

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			H&Q HEALTHCARE INVESTORS
		CENTRAL INDEX KEY:			0000805267
		STANDARD INDUSTRIAL CLASSIFICATION:	UNKNOWN SIC - 0000 [0000]
		IRS NUMBER:				046564285
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			0930

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		50 ROWES WHARF
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02110
		BUSINESS PHONE:		6175740537

	MAIL ADDRESS:	
		STREET 1:		50 ROWES WHARF
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02110
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<DESCRIPTION>LJL BIOSYSTEMS FORM SC 13G/A
<TEXT>




                                                   -----------------------------
                                                            OMB APPROVAL
                                                   -----------------------------
                                                   OMB Number:        3235-0145
                                                   Expires:
                                                   Estimated average burden
                                                   hours per response .... 14.90
                                                   -----------------------------


                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                  SCHEDULE 13G


                   Under the Securities Exchange Act of 1934

                               (Amendment No. 2)*


                                 LJL Biosystems
                   ------------------------------------------
                                (Name of Issuer)


                                     Common
                   ------------------------------------------
                         (Title of Class of Securities)


                                   0501873103
                   ------------------------------------------
                                 (CUSIP Number)


Check the following box if a fee is being paid with this statement [ ]. (A fee
is not required only if the filing person: (1) has a previous statement on file
reporting beneficial ownership of more than five percent of the class of
securities described in Item 1; and (2) has filed no amendment subsequent
thereto reporting beneficial ownership of five percent or less of such class.)
(See Rule 13d-7.)

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).



SEC 1745 (2/92)                Page 1 of 4 pages


<PAGE>



- ----------------------------------                   ---------------------------
| CUSIP NO.  0501873103          |        13G        |  Page  2  of  4  Pages  |
|           -------------        |                   |       ---    ---        |
- ----------------------------------                   ---------------------------

|--------|---------------------------------------------------------------------|
|   1    |  NAME OF REPORTING PERSON                                           |
|        |  S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON                  |
|        |                                                                     |
|        |  Hambrecht & Quist Capital Management Incorporated                  |
|--------|---------------------------------------------------------------------|
|   2    |  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*         (a) [ ]  |
|        |                                                            (b) [X]  |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   3    |  SEC USE ONLY                                                       |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|   4    |  CITIZENSHIP OR PLACE OF ORGANIZATION                               |
|        |                                                                     |
|        |                                                                     |
|-----------------|--------|---------------------------------------------------|
|                 |   5    |  SOLE VOTING POWER                                |
|                 |        |  969,232                                          |
|     NUMBER OF   |--------|---------------------------------------------------|
|      SHARES     |   6    |  SHARED VOTING POWER                              |
|   BENEFICIALLY  |        |                                                   |
|     OWNED BY    |--------|---------------------------------------------------|
|       EACH      |   7    |  SOLE DISPOSITIVE POWER                           |
|    REPORTING    |        |                                                   |
|      PERSON     |--------|---------------------------------------------------|
|       WITH      |   8    |  SHARED DISPOSITIVE POWER                         |
|                 |        |                                                   |
|------------------------------------------------------------------------------|
|   9    |  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON       |
|        |                                                                     |
|        |  969,232                                                            |
|--------|---------------------------------------------------------------------|
|  10    |  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN  [ ] |
|        |  SHARES*                                                            |
|        |                                                                     |
|--------|---------------------------------------------------------------------|
|  11    |  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)                  |
|        |  7.63%                                                              |
|--------|---------------------------------------------------------------------|
|  12    |  TYPE OF REPORTING PERSON*                                          |
|        |  IA                                                                 |
- --------------------------------------------------------------------------------
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


                                Page 2 of 4 pages

<PAGE>


                              SCHEDULE 13G EXHIBIT

Item 1.

     LJL Biosystems
     405 Tasman Drive
     Sunnyvale, CA 94089


Item 2.

     Hambrecht & Quist Capital Management Incorporated
     50 Rowes Wharf - 4th Floor
     Boston, MA  02110-3328
     (California corporation)

     Common stock
     CUSIP: 0501873103


Item 3.

     (e)  Investment Adviser


Item 4.

     Hambrecht & Quist Capital Management Incorporated ("HQCM") disclaims any
     beneficial interest in the shares reported in this Schedule 13G. Moreover,
     HQCM is of the view that the client accounts that it manages are not acting
     as a "group" for purposes of Section 13(d) under the Securities and
     Exchange Act of 1934 (the "1934 Act") and that it and such clients are not
     otherwise required to attribute to each other the "beneficial ownership" of
     securities "beneficially owned" under Rule 13d-3 promulgated under the 1934
     Act. Therefore, HQCM is of the view that the shares held in such accounts
     should not be aggregated for purposes of Section 13(d). However, HQCM is
     making this filing on a voluntary basis as if all the shares are
     beneficially owned by HQCM on a joint basis.

     969,232 shares of Common stock  beneficially owned
     7.63% of Common
     969,232 sole voting power (i) and sole dispositive power (iii)


Item 5.

     N/A


Item 6.

     N/A


Item 7.

     N/A


Item 8.

     N/A


                                       E-1
<PAGE>


Item 9.

     N/A


Item 10.

     By signing below I certify that, to the best of my knowledge and belief,
     the securities referred to above were acquired in the ordinary course of
     business and were not acquired for the purpose of and do not have the
     effect of changing or influencing the control of the issuer of such
     securities and were not acquired in connection with or as a participant in
     any transaction having such purposes or effect.

     After reasonable inquiry and to the best of my knowledge and belief, I
     certify that the information set forth in this statement is true, complete
     and correct.


     Date:        2/14/00
                  -------------------------------------------------

     Signature:   /s/ Kim Carroll
                  -------------------------------------------------
     Name/Title:  Kim Carroll, Vice President
                  Hambrecht & Quist Capital Management Incorporated



                                       E-2



</TEXT>
</DOCUMENT>
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