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Leases - Additional Information (Detail) |  | 12 Months Ended
--- | --- | ---
Mar. 08, 2022 USD ($) ft² | Dec. 31, 2021 USD ($) ft² Tranche Lease | Dec. 31, 2020 USD ($)
Disclosure Of Leases [Line Items] |  |  |
Loan facility term |  | 5 years |
Operating lease weighted average remaining lease term |  | 3 years 4 months 24 days |
Operating lease weighted average discount rate |  | 12.50% |
Operating lease expense |  | $ 885,000 | $ 852,000
Variable lease cost |  | 30,000 | 36,000
Operating lease payments |  | 920,000 | 867,000
Finance lease, amortization expense of ROU asset |  | 151,000 | 52,000
Interest expense on finance lease liability |  | 23,000 | 9,000
Finance lease, operating cash flows |  | 23,000 | 9,000
Finance lease, financing cash flows |  | $ 146,000 | $ 49,000
Finance lease, weighted average Remaining term |  | 1 year 3 months 18 days |
Finance lease, weighted average discount rate, percent |  | 12.50% |
Caladrius [Member] |  |  |
Disclosure Of Leases [Line Items] |  |  |
Additional subleased property office area | ft² |  | 1,381 |
Basking Ridge Office Space [Member] |  |  |
Disclosure Of Leases [Line Items] |  |  |
Number of renewal options | Tranche |  | 2 |
Laboratory Equipment [Member] |  |  |
Disclosure Of Leases [Line Items] |  |  |
Number of finance leases | Lease |  | 3 |
First Lab Equipment [Member] |  |  |
Disclosure Of Leases [Line Items] |  |  |
Lease expiration month year |  | 2021-12 |
Second Lab Equipment [Member] |  |  |
Disclosure Of Leases [Line Items] |  |  |
Lease expiration month year |  | 2022-12 |
Third Lab Equipment [Member] |  |  |
Disclosure Of Leases [Line Items] |  |  |
Lease expiration month year |  | 2023-06 |
Massachusetts [Member] | Maximum [Member] |  |  |
Disclosure Of Leases [Line Items] |  |  |
Construction allowance |  | $ 670,750 |
Massachusetts [Member] | Original Lease [Member] |  |  |
Disclosure Of Leases [Line Items] |  |  |
Area of leased office and laboratory space | ft² |  | 13,650 |
Original lease term |  | 5 years |
Lease expiration month year |  | 2019-04 |
Massachusetts [Member] | Second Amendment Lease [Member] |  |  |
Disclosure Of Leases [Line Items] |  |  |
Lease commencement date |  | Sep. 10, 2018 |
Lease term expiration date |  | May 31, 2025 |
Additional Space leased | ft² |  | 6,590 |
Irrevocable standby letter of credit |  | $ 150,000 |
Massachusetts [Member] | Third Amendment Lease [Member] |  |  |
Disclosure Of Leases [Line Items] |  |  |
Area of leased office and laboratory space | ft² |  | 1,409 |
Lease commencement date |  | Jul. 01, 2021 |
Lease term expiration date |  | May 31, 2025 |
Massachusetts [Member] | Fourth Amendment Lease [Member] | Subsequent Event [Member] |  |  |
Disclosure Of Leases [Line Items] |  |  |
Area of leased office and laboratory space | ft² | 13,650 |  |
Lease term expiration date | May 31, 2028 |  |
Additional Space leased | ft² | 11,999 |  |
Termination portion of the lease | ft² | 7,999 |  |
Lease termination date | May 31, 2025 |  |
Massachusetts [Member] | Fourth Amendment Lease [Member] | Maximum [Member] | Subsequent Event [Member] |  |  |
Disclosure Of Leases [Line Items] |  |  |
Construction allowance | $ 555,960 |  |
NEW JERSEY | Basking Ridge Office Space [Member] |  |  |
Disclosure Of Leases [Line Items] |  |  |
Lease expiration month year |  | 2022-06 |
Area of leased office space | ft² |  | 3,000 |
Lease inception month year |  | 2017-07 |
Additional lease renewal option period |  | 5 years |
Lease renewal rate at 95% of market rent at time of renewal |  | 95.00% |

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