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Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2021
Income Tax Disclosure [Abstract] |
Components of Loss Before Income Taxes | The components of loss before income taxes are as follows (in thousands):
|  | Year Ended December 31, |  |  | Year Ended December 31, |
|  | 2021 |  |  | 2020 |
U.S. operations |  | $ | (58,517 | ) |  | $ | (45,492 | )
Non-U.S. operations |  |  | 100 |  |  |  | 98 |
Loss before income taxes |  | $ | (58,417 | ) |  | $ | (45,394 | )
Difference Between Expected Income Tax Benefit and Actual Income Tax Benefit | The difference between the Company’s expected income tax benefit, as computed by applying the blended statutory U.S. federal tax rate of 21% for the year ended December 31, 2021 and 21% for the year ended December 31, 2020, to loss before income taxes, and actual income tax benefit is reconciled in the following table (in thousands):
|  | Year Ended December 31, |  |  | Year Ended December 31, |
|  | 2021 |  |  | 2020 |
Income tax benefit at statutory rate |  | $ | (12,268 | ) |  | $ | (9,533 | )
State income taxes, net of federal benefit |  |  | (2,890 | ) |  |  | (2,760 | )
Non-U.S. income tax rate differential |  |  | — |  |  |  | (8 | )
Change in fair value of derivative |  |  | — |  |  | — |
Change in federal tax rate |  |  | — |  |  | — |
Research and development tax credits |  |  | (693 | ) |  |  | (403 | )
Permanent items |  |  | 729 |  |  |  | 288 |
Changes in valuation allowance |  |  | 15,748 |  |  |  | 13,068 |
Other, net |  |  | (626 | ) |  |  | (652 | )
Income tax benefit |  | $ | — |  |  | $ | — |
Significant Components of Deferred Income Taxes | The significant components of deferred income taxes are as follows (in thousands):
|  | December 31, |  |  | December 31, |
|  | 2021 |  |  | 2020 |
Deferred tax assets: |  |  |  |  |  |  |  |
Net operating loss carryforwards |  | $ | 84,026 |  |  | $ | 74,876 |
Deferred revenue |  |  | 4,270 |  |  |  | 150 |
Lease liability |  |  | 722 |  |  |  | 806 |
Stock-based compensation |  |  | 7,822 |  |  |  | 6,847 |
Tax credits |  |  | 5,446 |  |  |  | 4,503 |
Other |  |  | 3,005 |  |  |  | 2,514 |
Total deferred tax assets |  |  | 105,291 |  |  |  | 89,696 |
Deferred tax liabilities: |  |  |  |  |  |  |  |
Intangible assets |  |  | 5,963 |  |  |  | 6,087 |
Right-of-use assets |  |  | 615 |  |  |  | 713 |
Total deferred tax liabilities |  |  | 6,578 |  |  |  | 6,800 |
Deferred tax assets, net |  |  | 98,713 |  |  |  | 82,896 |
Valuation allowance |  |  | 98,713 |  |  |  | 82,896 |
Total deferred tax liability |  | $ | — |  |  | $ | — |

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- Definition Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=121826272&loc=d3e32537-109319 + Details
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- Definition Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=121826272&loc=d3e32687-109319 + Details
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