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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2021 | Dec. 31, 2020
Cash flows from operating activities: |  |
Net loss | $ (58,417) | $ (45,394)
Adjustments to reconcile net loss to cash flows used in operating activities: |  |
Amortization of intangible assets | 2,460 | 2,460
Depreciation of property and equipment | 311 | 189
Amortization of debt discount | 628 | 745
Non-cash interest expense | 0 | 977
(Gain) loss on extinguishment of debt | (2,065) | 905
Provision for excess and obsolescence inventory | 1,278 | 0
Stock-based compensation | 7,447 | 5,547
Changes in operating assets and liabilities: |  |
Accounts receivable and other current assets | (10,603) | 4,846
Inventory | 1,347 | (3,200)
Accounts payable and accrued expenses | 8,476 | 1,872
Right-of-use assets and operating lease liabilities | (28) | 72
Deferred revenue | (931) | 16,546
Net cash used in operating activities | (50,097) | (14,435)
Cash flows from investing activities: |  |
Purchases of marketable securities | (32,965) | 0
Purchases of property and equipment | (156) | (362)
Net cash used in investing activities | (33,121) | (362)
Cash flows from financing activities: |  |
Proceeds from issuance of stock and pre-funded warrants, net of issuance costs | 216,825 | 49,918
Proceeds under paycheck protection program loan | 0 | 2,041
Payment of long-term debt principal | 0 | (13,794)
Payment of extinguishment of debt costs | 0 | (828)
Net settlement of stock units to satisfy statutory tax withholding | (150) | (90)
Proceeds from exercise of stock options | 373 | 294
Principal payments on finance lease obligations | (146) | (49)
Net cash provided by financing activities | 216,902 | 37,492
Effect of foreign exchange rate changes on cash and cash equivalents | 0 | 0
Net increase (decrease) in cash, cash equivalents and restricted cash | 133,684 | 22,695
Cash, cash equivalents and restricted cash at beginning of year | 45,059 | 22,364
Cash, cash equivalents and restricted cash at end of year | 178,743 | 45,059
Supplemental cash flow information: |  |
Cash interest paid | 4,846 | 5,510
Supplemental disclosure of non-cash investing and financing activities: |  |
Stock issuance costs | 294 | 0
Accrued term loan exit fee | 0 | 122
Payments forgiven under paycheck protection program loan | $ 2,041 | $ 0

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