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Leases - Additional Information (Detail)
 12 Months Ended
Mar. 08, 2022
USD ($)
ft²
Dec. 31, 2021
USD ($)
ft²
Tranche
Lease
Dec. 31, 2020
USD ($)
Disclosure Of Leases [Line Items]      
Loan facility term   5 years  
Operating lease weighted average remaining lease term   3 years 4 months 24 days  
Operating lease weighted average discount rate   12.50%  
Operating lease expense   $ 885,000 $ 852,000
Variable lease cost   30,000 36,000
Operating lease payments   920,000 867,000
Finance lease, amortization expense of ROU asset   151,000 52,000
Interest expense on finance lease liability   23,000 9,000
Finance lease, operating cash flows   23,000 9,000
Finance lease, financing cash flows   $ 146,000 $ 49,000
Finance lease, weighted average Remaining term   1 year 3 months 18 days  
Finance lease, weighted average discount rate, percent   12.50%  
Caladrius [Member]      
Disclosure Of Leases [Line Items]      
Additional subleased property office area | ft²   1,381  
Basking Ridge Office Space [Member]      
Disclosure Of Leases [Line Items]      
Number of renewal options | Tranche   2  
Laboratory Equipment [Member]      
Disclosure Of Leases [Line Items]      
Number of finance leases | Lease   3  
First Lab Equipment [Member]      
Disclosure Of Leases [Line Items]      
Lease expiration month year   2021-12  
Second Lab Equipment [Member]      
Disclosure Of Leases [Line Items]      
Lease expiration month year   2022-12  
Third Lab Equipment [Member]      
Disclosure Of Leases [Line Items]      
Lease expiration month year   2023-06  
Massachusetts [Member] | Maximum [Member]      
Disclosure Of Leases [Line Items]      
Construction allowance   $ 670,750  
Massachusetts [Member] | Original Lease [Member]      
Disclosure Of Leases [Line Items]      
Area of leased office and laboratory space | ft²   13,650  
Original lease term   5 years  
Lease expiration month year   2019-04  
Massachusetts [Member] | Second Amendment Lease [Member]      
Disclosure Of Leases [Line Items]      
Lease commencement date   Sep. 10, 2018  
Lease term expiration date   May 31, 2025  
Additional Space leased | ft²   6,590  
Irrevocable standby letter of credit   $ 150,000  
Massachusetts [Member] | Third Amendment Lease [Member]      
Disclosure Of Leases [Line Items]      
Area of leased office and laboratory space | ft²   1,409  
Lease commencement date   Jul. 01, 2021  
Lease term expiration date   May 31, 2025  
Massachusetts [Member] | Fourth Amendment Lease [Member] | Subsequent Event [Member]      
Disclosure Of Leases [Line Items]      
Area of leased office and laboratory space | ft² 13,650    
Lease term expiration date May 31, 2028    
Additional Space leased | ft² 11,999    
Termination portion of the lease | ft² 7,999    
Lease termination date May 31, 2025    
Massachusetts [Member] | Fourth Amendment Lease [Member] | Maximum [Member] | Subsequent Event [Member]      
Disclosure Of Leases [Line Items]      
Construction allowance $ 555,960    
NEW JERSEY | Basking Ridge Office Space [Member]      
Disclosure Of Leases [Line Items]      
Lease expiration month year   2022-06  
Area of leased office space | ft²   3,000  
Lease inception month year   2017-07  
Additional lease renewal option period   5 years  
Lease renewal rate at 95% of market rent at time of renewal   95.00%