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Income Taxes - Difference Between Expected Income Tax Benefit and Actual Income Tax Benefit (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Income Tax Disclosure [Abstract]
Income tax benefit at statutory rate	$ (12,268)	$ (9,533)
State income taxes, net of federal benefit	(2,890)	(2,760)
Non-U.S. income tax rate differential	0	(8)
Change in fair value of derivative	0	0
Change in federal tax rate	0	0
Research and development tax credits	(693)	(403)
Permanent items	729	288
Changes in valuation allowance	15,748	13,068
Other, net	(626)	(652)
Income tax expense (benefit)	$ 0	$ 0

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Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to increase (decrease) in the valuation allowance for deferred tax assets.

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