<SEC-DOCUMENT>0001477932-25-008506.txt : 20251119
<SEC-HEADER>0001477932-25-008506.hdr.sgml : 20251119
<ACCEPTANCE-DATETIME>20251119210339
ACCESSION NUMBER:		0001477932-25-008506
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20251117
FILED AS OF DATE:		20251119
DATE AS OF CHANGE:		20251119

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Ainscow Robert
		CENTRAL INDEX KEY:			0001951275
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-41555
		FILM NUMBER:		251500820

	MAIL ADDRESS:	
		STREET 1:		C/O ASP ISOTOPES INC.
		STREET 2:		1101 PENNSYLVANIA AVENUE NW, SUITE 300
		CITY:			WASHINGTON DC
		STATE:			DC
		ZIP:			20004

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ASP Isotopes Inc.
		CENTRAL INDEX KEY:			0001921865
		STANDARD INDUSTRIAL CLASSIFICATION:	MISCELLANEOUS CHEMICAL PRODUCTS [2890]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		EIN:				872618235
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		601 PENNSYLVANIA AVENUE NW
		STREET 2:		SOUTH BUILDING, SUITE 900
		CITY:			WASHINGTON
		STATE:			DC
		ZIP:			20004
		BUSINESS PHONE:		202-756-2245

	MAIL ADDRESS:	
		STREET 1:		601 PENNSYLVANIA AVENUE NW
		STREET 2:		SOUTH BUILDING, SUITE 900
		CITY:			WASHINGTON
		STATE:			DC
		ZIP:			20004
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>form4.xml
<DESCRIPTION>FORM 4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0508</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2025-11-17-05:00</periodOfReport>

    <notSubjectToSection16>false</notSubjectToSection16>

    <issuer>
        <issuerCik>0001921865</issuerCik>
        <issuerName>ASP Isotopes Inc.</issuerName>
        <issuerTradingSymbol>ASPI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001951275</rptOwnerCik>
            <rptOwnerName>Ainscow Robert</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O ASP ISOTOPES INC.</rptOwnerStreet1>
            <rptOwnerStreet2>601 PENNSYLVANIA AVENUE NW SUITE 900</rptOwnerStreet2>
            <rptOwnerCity>WASHINGTON DC</rptOwnerCity>
            <rptOwnerState>DC</rptOwnerState>
            <rptOwnerZipCode>20004</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>false</isDirector>
            <isOfficer>true</isOfficer>
            <isTenPercentOwner>false</isTenPercentOwner>
            <isOther>false</isOther>
            <officerTitle>Interim CEO and COO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <aff10b5One>true</aff10b5One>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2025-11-17-05:00</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>false</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>67500</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>7.507</value>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1579693</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">Represents &quot;sell to cover&quot; sales effected pursuant to a Rule 10b5-1 trading plan adopted by the filing person on June 9, 2025 to cover tax withholding obligations in connection with the vesting of restricted stock awards.</footnote>
        <footnote id="F2">The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $7.215 to $7.85, inclusive. The reporting person undertakes to provide ASP Isotopes Inc. (the &quot;Company&quot;), any stockholder of the Company, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in Footnote 2.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Donald Ainscow, as attorney-in-fact</signatureName>
        <signatureDate>2025-11-19-05:00</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
