<SEC-DOCUMENT>0001628280-24-008117-index.html : 20240301
<SEC-HEADER>0001628280-24-008117.hdr.sgml : 20240301
<ACCEPTANCE-DATETIME>20240301080957
ACCESSION NUMBER:		0001628280-24-008117
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		5
REFERENCES 429:			333-267953
REFERENCES 429:			333-270400
FILED AS OF DATE:		20240301
DATE AS OF CHANGE:		20240301
EFFECTIVENESS DATE:		20240301

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Prime Medicine, Inc.
		CENTRAL INDEX KEY:			0001894562
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-277567
		FILM NUMBER:		24707045

	BUSINESS ADDRESS:	
		STREET 1:		21 ERIE ST.
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139
		BUSINESS PHONE:		617-465-0013

	MAIL ADDRESS:	
		STREET 1:		21 ERIE ST.
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8
<SEQUENCE>1
<FILENAME>prime-2024sx8.htm
<DESCRIPTION>S-8
<TEXT>
Document 1 - file: prime-2024sx8.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>2
<FILENAME>prime-2024sx8xex107filingf.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 2 - file: prime-2024sx8xex107filingf.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>3
<FILENAME>prime-2024sx8xex51opinion.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 3 - file: prime-2024sx8xex51opinion.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>4
<FILENAME>prime-2024sx8xex231consent.htm
<DESCRIPTION>EX-23.1
<TEXT>
Document 4 - file: prime-2024sx8xex231consent.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>logoa.jpg
<TEXT>
Document 5 - file: logoa.jpg

</DOCUMENT>
</SEC-DOCUMENT>