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Consolidated Statements Of Preferred Stock And Stockholders' Equity (Deficit) (USD $)	Accretion Of Series A [Member] Series A [Member] USD ($)	Accretion Of Series A [Member] Additional Paid-In Capital [Member] USD ($)	Accretion Of Series A [Member] USD ($)	Accretion Of Series B [Member] Series B [Member] USD ($)	Accretion Of Series B [Member] Additional Paid-In Capital [Member] USD ($)	Accretion Of Series B [Member] USD ($)	Series A [Member] Issuance Of Series A On February 22, 2006 [Member] USD ($)	Series A [Member] Issuance Of Series A On December 8, 2006 [Member] USD ($)	Series A [Member] Issuance For Notes Payable And Related Accrued Interest On February 22, 2006 [Member] USD ($)	Series A [Member] USD ($)	Series B [Member] Issuance For Series B On May 31, 2007 [Member] USD ($)	Series B [Member] Issuance For Series B On December 28, 2007 [Member] USD ($)	Series B [Member] USD ($)	Common Stock [Member] Common Conversion [Member]	Common Stock [Member] Notes And Related Accrued Interest [Member] USD ($)	Common Stock [Member] Cash, Net Of Offering Costs [Member]	Common Stock [Member] Issuance For Notes Payable and Related Accrued Interest On January 3, 2005 [Member]	Common Stock [Member] Issuance For Notes Payable And Related Accrued Interest On October 14, 2005 [Member]	Common Stock [Member] Issuance For Intellectual Property License Rights On October 14, 2005 [Member]	Common Stock [Member] Issuance For Intellectual Property License Rights On February 21, 2006 [Member]	Common Stock [Member] Issuance For Intellectual Property License Rights On February 22, 2006 [Member] USD ($)	Common Stock [Member] Issuance For Intellectual Property License Rights On June 23, 2006 [Member]	Common Stock [Member] Issuance For Intellectual Property License Rights On November 7, 2006 [Member]	Common Stock [Member] Issuance For Intellectual Property License Rights On January 18, 2007 [Member]	Common Stock [Member] Issuance For Intellectual Property License Rights On June 30, 2007 [Member]	Common Stock [Member] Issuance Of Common Stock For Commercial License Rights, On July 19, 2007 [Member] USD ($)	Common Stock [Member] Issuance Of Shares To Executive Subject To Repurchase [Member]	Common Stock [Member] USD ($)	Additional Paid-In Capital [Member] Notes And Related Accrued Interest [Member] USD ($)	Additional Paid-In Capital [Member] Cash, Net Of Offering Costs [Member] USD ($)	Additional Paid-In Capital [Member] Issuance For Notes Payable and Related Accrued Interest On January 3, 2005 [Member] USD ($)	Additional Paid-In Capital [Member] Issuance For Notes Payable And Related Accrued Interest On October 14, 2005 [Member] USD ($)	Additional Paid-In Capital [Member] Issuance For Intellectual Property License Rights On October 14, 2005 [Member] USD ($)	Additional Paid-In Capital [Member] Issuance For Intellectual Property License Rights On February 21, 2006 [Member] USD ($)	Additional Paid-In Capital [Member] Issuance For Intellectual Property License Rights On February 22, 2006 [Member] USD ($)	Additional Paid-In Capital [Member] Issuance For Intellectual Property License Rights On June 23, 2006 [Member] USD ($)	Additional Paid-In Capital [Member] Issuance For Intellectual Property License Rights On January 18, 2007 [Member] USD ($)	Additional Paid-In Capital [Member] Issuance For Intellectual Property License Rights On June 30, 2007 [Member] USD ($)	Additional Paid-In Capital [Member] USD ($)	Deficit Accumulated During Development Stage [Member] USD ($)	Notes And Related Accrued Interest [Member] USD ($)	Cash, Net Of Offering Costs [Member] USD ($)	Issuance For Notes Payable and Related Accrued Interest On January 3, 2005 [Member] USD ($)	Issuance For Notes Payable And Related Accrued Interest On October 14, 2005 [Member] USD ($)	Issuance For Intellectual Property License Rights On October 14, 2005 [Member] USD ($)	Issuance For Intellectual Property License Rights On February 21, 2006 [Member] USD ($)	Issuance For Intellectual Property License Rights On February 22, 2006 [Member] USD ($)	Issuance For Intellectual Property License Rights On June 23, 2006 [Member] USD ($)	Issuance For Intellectual Property License Rights On January 18, 2007 [Member] USD ($)	Issuance For Intellectual Property License Rights On June 30, 2007 [Member] USD ($)	Total USD ($)
Beginning Balance, value at Dec. 17, 2001
Net loss																																								$ (116,000)											$ (116,000)
Issuance of common stock for cash, net of offering costs, shares																15,529
Issuance of common stock for cash, net of offering costs, value																														1,000												1,000
Ending Balance, value at Dec. 31, 2003																																							1,000	(116,000)											(115,000)
Ending Balance, shares at Dec. 31, 2003																												15,529
Net loss																																								(511,000)											(511,000)
Issuance of common stock for cash, net of offering costs, shares																118,319
Issuance of common stock for cash, net of offering costs, value																														7,000												7,000
Ending Balance, value at Dec. 31, 2004																																							8,000	(627,000)											(619,000)
Ending Balance, shares at Dec. 31, 2004																												133,848
Net loss																																								(1,459,000)											(1,459,000)
Issuance of common stock for cash, net of offering costs, shares																17,533	17,867	186,571	5,419
Issuance of common stock for cash, net of offering costs, value																														1,000	1,000	1,354,000	44,000									1,000	1,000	1,354,000	44,000
Ending Balance, value at Dec. 31, 2005																																							1,408,000	(2,086,000)											(678,000)
Beginning Balance, shares at Dec. 31, 2005																												361,238
Offering costs	17,000									(98,000)																													(17,000)												(17,000)
Share-based compensation																																							39,000												39,000
Issuance of common stock upon exercise of stock options, for cash, value																																							3,000												3,000
Net loss																																								(5,241,000)											(5,241,000)
Issuance of common stock for cash, net of offering costs, shares							5,727,354	3,074,086	420,817											104,229	83,443	15,028	229					48,111
Issuance of common stock for cash, net of offering costs, value							9,316,000	5,000,000	684,000												1,000													75,000	59,000	15,000										75,000	60,000	15,000
Ending Balance, value at Dec. 31, 2006										14,919,000																		1,000											1,582,000	(7,327,000)											(5,744,000)
Ending Balance, shares at Dec. 31, 2006										9,222,257																		612,278
Offering costs	19,000	(19,000)	(19,000)	18,000	(18,000)	(18,000)							(147,000)
Share-based compensation																																							50,000												50,000
Issuance of common stock upon exercise of stock options, for cash, shares																												13,359											16,000
Issuance of common stock upon exercise of stock options, for cash, value																																																			16,000
Net loss																																								(13,994,000)											(13,994,000)
Issuance of common stock for cash, net of offering costs, shares											3,688,902	2,766,677												7,817	3,852		83,490
Issuance of common stock for cash, net of offering costs, value											9,000,000	9,000,000														16,698											13,000	7,000											13,000	7,000
Ending Balance, value at Dec. 31, 2007										14,938,000			17,871,000															1,000											1,631,000	(21,321,000)											(19,689,000)
Ending Balance, shares at Dec. 31, 2007										9,222,257			6,455,579															737,494
Offering costs	20,000	(20,000)	(20,000)	36,000	(36,000)	(36,000)
Share-based compensation																																							545,000												545,000
Estimated fair value of warrants issued in connection with convertible notes payable																																							399,000												399,000
Issuance of common stock upon exercise of stock options, for cash, shares																												216,926
Issuance of common stock upon exercise of stock options, for cash, value																																							54,000												54,000
Net loss																																								(19,431,000)											(19,431,000)
Ending Balance, value at Dec. 31, 2008										14,958,000			17,907,000															1,000											2,573,000	(40,752,000)											(38,178,000)
Ending Balance, shares at Dec. 31, 2008										9,222,257			6,455,579															954,420
Offering costs	42,000	(42,000)	(42,000)	93,000	(93,000)	(93,000)
Share-based compensation																																							845,000												845,000
Issuance of common stock upon exercise of stock options, for cash, shares																												63,123
Issuance of common stock upon exercise of stock options, for cash, value																																							114,000												114,000
Net loss																																								(9,138,000)											(9,138,000)
Adjustment for fractional shares on common conversion														(39)														(609)
Deemed preferred stock dividend for additional common shares issuable under anti-dilution provision													781,000																										(781,000)												(781,000)
Conversion of preferred stock, shares										(9,222,257)			(6,455,579)															3,042,740
Conversion of preferred stock and convertible notes and related accrued interest, value										(15,000,000)			(18,781,000)		1,000													3,000	8,500,000										33,778,000		8,501,000										33,781,000
Restricted stock release from restriction																																							75,000												75,000
Conversion of convertible notes and related accrued interest, shares															872,792
Conversion of warrants for preferred stock																																							36,000												36,000
Merger with Nuvelo, Inc., value																												3,000											11,910,000												11,913,000
Merger with Nuvelo, Inc., shares																												2,686,957
Issuance of common stock under employee stock purchase plan and upon vesting of restricted stock units, shares																												1,064
Issuance of common stock under employee stock purchase plan and upon vesting of restricted stock units, value																																							2,000												2,000
Estimated fair value of warrants issued in connection with lease termination																																							377,000												377,000
Ending Balance, value at Dec. 31, 2009																												8,000											57,294,000	(49,890,000)											7,412,000
Ending Balance, shares at Dec. 31, 2009																												7,620,448
Share-based compensation																																							458,000												458,000
Issuance of common stock upon exercise of stock options, for cash, shares																												49,487
Issuance of common stock upon exercise of stock options, for cash, value																																							139,000												139,000
Net loss																																								(8,420,000)											(8,420,000)
Issuance of common stock for cash, net of offering costs, shares																												1,164,600
Issuance of common stock for cash, net of offering costs, value																												1,000											7,181,000												7,182,000
Ending Balance, value at Dec. 31, 2010																												9,000											65,072,000	(58,310,000)											6,771,000
Ending Balance, shares at Dec. 31, 2010																												8,834,535
Share-based compensation																																							153,000												153,000
Net loss																																								(1,912,000)											(1,912,000)
Issuance of common stock for cash, net of offering costs, shares																												1,681,172
Issuance of common stock for cash, net of offering costs, value																												2,000											2,531,000												2,533,000
Ending Balance, value at Jun. 30, 2011																												$ 11,000											$ 67,756,000	$ (60,222,000)											$ 7,545,000
Ending Balance, shares at Jun. 30, 2011																												10,515,707

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