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Share-based Compensation (Tables)

6 Months Ended

Jun. 30, 2012

Share-based Compensation [Abstract]

Non-cash, share-based compensation expense

		Three Months Ended June 30,								Six Months Ended June 30,								Period from December 17, 2001 (date of inception) to June 30, 2012
		2012				2011				2012				2011
Research and Development		$	25			$	30			$	51			$	60			$	547
Selling, General and Administrative			53				45				118				93				1,517
Restructuring			—				—				—				—				387
Total		$	78			$	75			$	169			$	153			$	2,451

Estimated fair values of employee stock options

		Three Months Ended June 30,						Six Months Ended June 30,
		2012		2011				2012				2011
Expected term		*			5.8 years				5.3 years				5.8 years
Expected volatility		*			110	%			108	%			110	%
Risk-free interest rate		*			2.20	%			0.15	%			2.20	%
Expected dividend yield		*			0	%			0	%			0	%
Weighted-average grant date fair value per share		*		$	1.83			$	0.78			$	1.83

*No options were granted during the three months ended June 30, 2012.

Stock option transactions under all plans

		# of Options				Weighted Average Exercise Price				Weighted Average Remaining Contractual Term (in years)				Aggregate Intrinsic Value
Options outstanding at December 31, 2011			864,238			$	3.20				6.82			$	23,894
Changes during the period:
Granted			35,000				1.00
Exercised			—				—
Forfeited, cancelled or expired			(15,668	)			4.91
Options outstanding at June 30, 2012			883,570			$	3.08				6.54			$	461
Options exercisable at June 30, 2012			692,698			$	3.20				6.12			$	461
Options vested and expected to vest			872,641			$	3.09				6.53			$	461

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- Definition

Tabular disclosure of the allocation of equity-based compensation costs to a given line item on the balance sheet and income statement for the period. This may include the reporting line for the costs and the amount capitalized and expensed.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Statement of Financial Accounting Standard (FAS)

-Number 123R

-Paragraph A240

-Subparagraph g(1)

-LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy.



Reference 2: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Staff Accounting Bulletin (SAB)

-Number Topic 14

-Section F



Reference 3: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 718

-SubTopic 10

-Section 50

-Paragraph 1

-Subparagraph (b)

-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901



Reference 4: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 718

-SubTopic 10

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-Paragraph 2

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Reference 5: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Statement of Financial Accounting Standard (FAS)

-Number 123R

-Paragraph 64

-Subparagraph b

-LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy.



Reference 6: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 718

-SubTopic 10

-Section S99

-Paragraph 1

-Subparagraph (SAB TOPIC 14.F)

-URI http://asc.fasb.org/extlink&oid=6793087&loc=d3e301413-122809

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- Definition

Tabular disclosure of share-based compensation plans that may be presented in a single table for outstanding, vested and expected to vest, and exercisable awards. The information that may be disclosed in this table may include, but is not limited to, number of shares, weighted average exercise price, weighted average remaining contractual life, and aggregate intrinsic value.

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- Definition

Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 718

-SubTopic 10

-Section 50

-Paragraph 2

-Subparagraph (f)(2)

-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901

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