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Commitments and Contingencies (Details Textual) (USD $)
 1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended 129 Months Ended 1 Months Ended
Jul. 31, 2008
Feb. 28, 2007
Sep. 30, 2012
Sep. 30, 2012
Sep. 30, 2011
Dec. 31, 2011
Dec. 31, 2010
Sep. 30, 2012
Jun. 14, 2011
sqft
Feb. 08, 2008
sqft
Feb. 29, 2004
Feb. 29, 2004
Nuvelo [Member]
Upfront fee paid in cash                       $ 500,000
Upfront fee paid                       4,000,000
Issuance of common stock for cash, net of offering costs, value           4,017,000 7,182,000         3,500,000
Commitments and Contingencies (Textual) [Abstract]                        
Area of office facilities taken on lease                 4,500 15,000    
Lease term       5 years                
Extended lease term       3 years                
Rights to extend term       Two additional three year periods                
Lease agreement payment       200,000                
Tenant improvement reimbursements       593,000                
Unamortized deferred rent     24,000 24,000       24,000        
Rent expense       36,000 124,000              
Operating leases rent expense net since inception               503,000        
Allow to terminate agreement notice period     3 months                  
Term of license agreement   10 years                    
Share Issued   16,698                    
Milestone payment made by company 500,000                      
Expected milestone payments upon approval 8,000,000                      
Another expected milestone payments upon approval 5,000,000                      
Milestone payment due period 6 months                      
Minimum percentage of royalty obligation 12.50%                      
Maximum percentage of royalty obligation 25.00%                      
Percentage of royalty obligated to pay under its original license agreement 5.00%                      
Minimum percentage of range of royalties that can be buy down 12.50%                      
Maximum percentage of range of royalties that can be buy down 17.00%                      
Future milestone payments                     2,500,000  
Maximum future milestone payments                     $ 23,500,000