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Stock-based Compensation (Tables) | 12 Months Ended
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Dec. 31, 2012
Stock-based Compensation [Abstract] |
Estimated weighted average grant date fair value per share |
|  | Years Ended December 31, |
|  | 2012 |  |  | 2011 |
Expected term |  |  | 5.3 years |  |  |  | 5.8 years |
Expected volatility |  |  | 108 | % |  |  | 110 | %
Risk-free interest rate |  |  | 0.15 | % |  |  | 2.20 | %
Expected dividend yield |  |  | 0 | % |  |  | 0 | %
Weighted-average grant date fair value per share |  | $ | 4.68 |  |  | $ | 10.95 |
Summary of stock option activities |
|  | For the years ended December 31, |
|  | 2012 |  |  | 2011 |
|  | # of Options |  |  | Weighted Average Exercise Price |  |  | # of Options |  |  | Weighted Average Exercise Price |
Options outstanding, beginning of period |  |  | 144,039 |  |  | $ | 19.20 |  |  |  | 158,873 |  |  | $ | 191.22 |
Granted |  |  | 5,833 |  |  |  | 6.00 |  |  |  | 27,450 |  |  |  | 13.44 |
Exercised |  |  | — |  |  |  | 0.00 |  |  |  | (188 | ) |  |  | 7.86 |
Forfeited and cancelled |  |  | (5,853 | ) |  |  | 27.96 |  |  |  | (42,096 | ) |  |  | 664.86 |
Options outstanding, end of period |  |  | 144,019 |  |  | $ | 18.28 |  |  |  | 144,039 |  |  | $ | 19.20 |
Options exercisable, end of period |  |  | 125,666 |  |  | $ | 18.77 |  |  |  | 102,691 |  |  | $ | 20.10 |
Options vested and expected to vest |  |  | 142,227 |  |  | $ | 18.30 |  |  |  |  |  |  |  |  |
Summary of stock options outstanding and exercisable |
|  |  |  |  |  |  | Options Outstanding |  |  | Options Exercisable |
Range of Exercise Prices |  |  | Number Outstanding |  |  | Weighted Average Remaining Contractual Term (in years) |  |  | Weighted Average Exercise Price |  |  | Number Exercisable |  |  | Weighted Average Exercise Price |
$0.36 |  | — |  | $ | 3.60 |  |  |  | 1,248 |  |  |  | 2.42 |  |  | $ | 3.13 |  |  |  | 1,248 |  |  | $ | 3.13 |
5.40 |  | — |  |  | 5.40 |  |  |  | 33,844 |  |  |  | 1.20 |  |  |  | 5.40 |  |  |  | 33,844 |  |  |  | 5.40 |
6.00 |  | — |  |  | 11.16 |  |  |  | 22,078 |  |  |  | 5.19 |  |  |  | 9.73 |  |  |  | 21,883 |  |  |  | 9.76 |
13.44 |  | — |  |  | 13.44 |  |  |  | 25,363 |  |  |  | 7.87 |  |  |  | 13.44 |  |  |  | 14,115 |  |  |  | 13.44 |
16.14 |  | — |  |  | 17.40 |  |  |  | 26,354 |  |  |  | 5.91 |  |  |  | 16.96 |  |  |  | 20,386 |  |  |  | 17.09 |
17.82 |  | — |  |  | 33.42 |  |  |  | 34,570 |  |  |  | 5.55 |  |  |  | 27.85 |  |  |  | 33,628 |  |  |  | 27.95 |
87.47 |  | — |  |  | 1,908.00 |  |  |  | 562 |  |  |  | 3.43 |  |  |  | 856.14 |  |  |  | 562 |  |  |  | 856.14 |
|  |  |  |  |  |  |  |  | 144,019 |  |  |  | 4.91 |  |  | $ | 18.28 |  |  |  | 125,666 |  |  | $ | 18.77 |
Non-cash, share-based compensation expense |
|  | Years Ended December 31, |  |  | Period from December 17, 2001 (date of inception) to December 31, 2012 |
|  | 2012 |  |  | 2011 |  |
Research and Development |  | $ | 94 |  |  | $ | 117 |  |  | $ | 590 |
Selling, General and Administrative |  |  | 212 |  |  |  | 191 |  |  |  | 1,611 |
Restructuring Expense |  |  | — |  |  |  | — |  |  |  | 387 |
Total |  | $ | 306 |  |  | $ | 308 |  |  | $ | 2,588 |

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- Definition Tabular disclosure of the allocation of equity-based compensation costs to a given line item on the balance sheet and income statement for the period. This may include the reporting line for the costs and the amount capitalized and expensed. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Statement of Financial Accounting Standard (FAS) -Number 123R -Paragraph A240 -Subparagraph g(1) -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Staff Accounting Bulletin (SAB) -Number Topic 14 -Section F Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Statement of Financial Accounting Standard (FAS) -Number 123R -Paragraph 64 -Subparagraph b -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB TOPIC 14.F) -URI http://asc.fasb.org/extlink&oid=6793087&loc=d3e301413-122809 + Details
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- Definition Tabular disclosure of share-based compensation plans that may be presented in a single table for outstanding, vested and expected to vest, and exercisable awards. The information that may be disclosed in this table may include, but is not limited to, number of shares, weighted average exercise price, weighted average remaining contractual life, and aggregate intrinsic value. + References No definition available. + Details
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- Definition Tabular disclosure of option exercise prices, by grouped ranges, including the upper and lower limits of the price range, the number of shares under option, weighted average exercise price and remaining contractual option terms. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Statement of Financial Accounting Standard (FAS) -Number 123R -Paragraph 64 -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Statement of Financial Accounting Standard (FAS) -Number 123R -Paragraph A240 -Subparagraph f -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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