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Commitments and Contingencies (Details) (USD $) | 1 Months Ended | 12 Months Ended | 132 Months Ended |  |
--- | --- | --- | --- | --- | ---
Jul. 31, 2008 | Dec. 31, 2012 | Dec. 31, 2011 | Dec. 31, 2012 | Jun. 14, 2011 sqft | Feb. 08, 2008 sqft
Commitments and Contingencies (Textual) [Abstract] |  |  |  |  |  |
Area of office facilities taken on lease |  |  |  |  | 4,500 | 15,000
Lease term |  | 5 years |  |  |  |
Extended lease term |  | 3 years |  |  |  |
Rights to extend term |  | Two additional three year periods |  |  |  |
Allow to terminate agreement notice period |  | 3 months |  |  |  |
Lease agreement payment |  | $ 200,000 |  |  |  |
Tenant improvement reimbursements |  | 593,000 |  |  |  |
Unamortized deferred rent |  | 16,000 |  | 16,000 |  |
Rent expense |  | 48,000 | 150,000 |  |  |
Operating Leases Rent expense Inception |  |  |  | 515,000 |  |
Lease expiry period |  | 2013-06 |  |  |  |
Minimum lease payments |  | 40,000 |  | 40,000 |  |
Milestone payment | 500,000 |  |  |  |  |
Expected milestone payments upon approval | 8,000,000 |  |  |  |  |
Another expected milestone payments upon approval | $ 5,000,000 |  |  |  |  |
Minimum percentage of royalty obligation | 12.50% |  |  |  |  |
Maximum percentage of royalty obligation | 25.00% |  |  |  |  |
Product sales levels royalty | 5.00% |  |  |  |  |
Minimum percentage of range of royalties that can be buy down | 12.50% |  |  |  |  |
Maximum percentage of range of royalties that can be buy down | 17.00% |  |  |  |  |
Milestone payment due period | 6 months |  |  |  |  |

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- Definition The cumulative difference between the rental payments required by a lease agreement and the rental income or expense recognized on a straight-line basis, or other systematic and rational basis more representative of the time pattern in which use or benefit is granted or derived from the leased property, expected to be recognized in income or expense over the term of the leased property by the lessor or lessee, respectively. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Statement of Financial Accounting Standard (FAS) -Number 13 -Paragraph 19 -Subparagraph b -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name FASB Technical Bulletin (FTB) -Number 85-3 -Paragraph 2 -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 840 -SubTopic 20 -Section 25 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=7501430&loc=d3e39896-112707 + Details
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