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Consolidated Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
 12 Months Ended 132 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2012
Cash flows used in operating activities:      
Net loss $ (4,320) $ (5,364) $ (67,994)
Adjustments to reconcile net loss to net cash used in operating activities:      
Gain on patent rights assignment   (2,000) (2,000)
Gain on bargain purchase     (25,282)
Depreciation and amortization 43 602 1,780
Non-cash interest expense     211
Share-based compensation 306 308 2,588
Issuance of warrants for lease termination     377
Accretion of liabilities     152
Impairment of property and equipment     125
Impairment of in-process research and development     6,000
Write-off of deferred tax liability     (2,281)
Gain on marketable securities available for sale     (263)
(Gain) loss from disposal of property and equipment   16 83
Other, net     267
Change in operating assets and liabilities (net of amounts acquired):      
Other current assets 278 14 2,820
Other assets 80 80 7,326
Accounts payable (195) (128) (2,125)
Accrued expenses and other liabilities (237) (220) (19,221)
Deferred rent (33) (267) 16
Net cash used in operating activities (4,078) (6,959) (97,421)
Cash flows provided by investing activities:      
Cash received from merger     30,392
Payment of deferred transaction costs     (1,186)
Purchase of property and equipment   (19) (1,879)
Proceeds from sale of marketable securities      15,369
Proceeds from sale of property and equipment   25 358
Proceeds from patent rights assignment   2,000 2,000
Net cash provided by investing activities   2,006 45,054
Cash flows provided by financing activities:      
Proceeds from issuance of convertible notes payable and related warrants for common stock     10,841
Proceeds from issuance of bank note payable     4,000
Proceeds from stock subject to repurchase     38
Proceeds from the issuance of preferred stock     32,316
Proceeds from the issuance of common stock 1,528 4,726 14,109
Repayment of principal on bank note payable     (4,000)
Repayment of principal on convertible notes payables     (105)
Repayment of principal on vendor finance agreement (134) (146) (280)
Net cash provided by financing activities 1,055 3,871 55,287
Net (decrease) increase in cash and cash equivalents (3,023) (1,082) 2,920
Cash and cash equivalents, beginning of period 5,943 7,025  
Cash and cash equivalents, end of period 2,920 5,943 2,920
Supplemental cash flow information:      
Interest paid 3 5 115
Supplemental disclosure of noncash investing and financing transactions:      
Accrued interest on notes payable converted to equity     163
Warrant issued in connection with credit facility     111
Accrued deferred transaction costs     482
Common Stock
      
Cash flows provided by financing activities:      
Payment of offering costs (339) (709) (1,386)
Preferred Stock
      
Cash flows provided by financing activities:      
Payment of offering costs     $ (246)