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The Company and Summary of Significant Accounting Policies (Details) (USD $) In Thousands, unless otherwise specified | 1 Months Ended | 12 Months Ended | 144 Months Ended | 0 Months Ended | 1 Months Ended | 12 Months Ended
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Mar. 04, 2013 | Dec. 31, 2013 Segment Patients | Dec. 31, 2012 | Dec. 31, 2013 | Feb. 07, 2014 Subsequent Event | Feb. 28, 2014 Two Zero One Four Equity Financings Subsequent Event Registered Direct Offering | Dec. 31, 2013 Phase 3 heart failure (HF) trial of Gencaro Patients
Company Development Stage and Basis of Presentation (Textual) [Abstract] |  |  |  |  |  |  |
Number of patients |  |  |  |  |  |  | 2,708
Number of patients company trial to enroll |  | 200 |  |  |  |  | 420
Number of years to complete the study |  | 2 years 6 months |  |  |  |  |
Loss from operations |  | $ (6,940) | $ (4,319) | $ (106,083) |  |  |
Cash flows from operations |  | (5,288) | (4,078) | (102,709) |  |  |
Fund raised through sale of convertible preferred and common stock |  | 19,300 |  | 10,841 |  |  |
Proceeds from the issuance of common stock |  | $ 1,741 | $ 1,528 | $ 15,850 | $ 7,900 | $ 7,900 |
Reverse stock split | 1-for-6 reverse split | 1-for-20 reverse stock split |  |  |  |  |
Merger conversion ratio |  | 0.16698070 |  |  |  |  |
Number of segments |  | 1 |  |  |  |  |
Cash and cash equivalents maturity period |  | 90 days or less |  |  |  |  |

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