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Consolidated Statements of Cash Flows (USD $) In Thousands, unless otherwise specified | 12 Months Ended | 144 Months Ended
--- | --- | ---
Dec. 31, 2013 | Dec. 31, 2012 | Dec. 31, 2013
Cash flows used in operating activities: |  |  |
Net loss | $ (6,939) | $ (4,320) | $ (74,933)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Gain on patent rights assignment |  |  | (2,000)
Gain on bargain purchase |  |  | (25,282)
Depreciation and amortization | 26 | 43 | 1,806
Non-cash interest expense |  |  | 211
Share-based compensation | 283 | 306 | 2,871
Issuance of warrants for lease termination |  |  | 377
Accretion of liabilities |  |  | 152
Impairment of property and equipment |  |  | 125
Impairment of in-process research and development |  |  | 6,000
Write-off of deferred tax liability |  |  | (2,281)
Gain on marketable securities available for sale |  |  | (263)
(Gain) loss from disposal of property and equipment |  |  | 83
Other, net |  |  | 267
Change in operating assets and liabilities (net of amounts acquired): |  |  |
Other current assets | 130 | 278 | 2,950
Other assets | 14 | 80 | 7,340
Accounts payable | 532 | (195) | (1,593)
Accrued expenses and other liabilities | 681 | (237) | (18,540)
Deferred rent | (15) | (33) | 1
Net cash used in operating activities | (5,288) | (4,078) | (102,709)
Cash flows provided by investing activities: |  |  |
Cash received from merger |  |  | 30,392
Payment of deferred transaction costs |  |  | (1,186)
Purchase of property and equipment | (32) |  | (1,911)
Proceeds from sale of marketable securities |  |  | 15,369
Proceeds from sale of property and equipment |  |  | 358
Proceeds from patent rights assignment |  |  | 2,000
Net cash (used in) provided by investing activities | (32) |  | 45,022
Cash flows provided by financing activities: |  |  |
Proceeds from issuance of convertible notes payable and related warrants for common stock | 19,300 |  | 10,841
Proceeds from issuance of bank note payable |  |  | 4,000
Proceeds from stock subject to repurchase |  |  | 38
Proceeds from the issuance of preferred stock | 20,000 |  | 52,316
Proceeds from the issuance of common stock | 1,741 | 1,528 | 15,850
Repayment of principal on bank note payable |  |  | (4,000)
Repayment of principal on convertible notes payables |  |  | (105)
Repayment of principal on vendor finance agreement | (174) | (134) | (454)
Net cash provided by financing activities | 19,156 | 1,055 | 74,443
Net (decrease) increase in cash and cash equivalents | 13,836 | (3,023) | 16,756
Cash and cash equivalents, beginning of period | 2,920 | 5,943 |
Cash and cash equivalents, end of period | 16,756 | 2,920 | 16,756
Supplemental cash flow information: |  |  |
Interest paid | 3 | 3 | 118
Supplemental disclosure of noncash investing and financing transactions: |  |  |
Accrued interest on notes payable converted to equity |  |  | 163
Warrant issued in connection with credit facility |  |  | 111
Accrued deferred transaction costs |  |  | 482
Preferred Stock |  |  |
Cash flows provided by financing activities: |  |  |
Payment of offering costs | (2,083) |  | (2,329)
Common Stock |  |  |
Cash flows provided by financing activities: |  |  |
Payment of offering costs | $ (328) | $ (339) | $ (1,714)

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- Definition Other income (expense) included in net income that results in no cash inflows or outflows in the period. Includes noncash adjustments to reconcile net income (loss) to cash provided by (used in) operating activities that are not separately disclosed. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 + Details
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- Definition The cash outflow associated with other payments to acquire businesses including deposit on pending acquisitions and preacquisition costs. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Investing Activities -URI http://asc.fasb.org/extlink&oid=6516133 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3213-108585 + Details
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- Definition Interest paid other than in cash for example by issuing additional debt securities. As a noncash item, it is added to net income when calculating cash provided by or used in operations using the indirect method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 + Details
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- Definition The cash outflow for cost incurred directly with the issuance of an equity security. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3291-108585 + Details
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- Definition The cash outflow associated with the acquisition of long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale; includes cash outflows to pay for construction of self-constructed assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Investing Activities -URI http://asc.fasb.org/extlink&oid=6516133 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3213-108585 + Details
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- Definition The cash inflow from the issuance of common stock, preferred stock, treasury stock, stock options, and other types of equity. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3255-108585 + Details
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