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Equity Financings and Warrants (Details Textual) (USD $) | 12 Months Ended | 144 Months Ended | 0 Months Ended | 1 Months Ended |  | 12 Months Ended |  | 12 Months Ended | 24 Months Ended |  | 12 Months Ended | 1 Months Ended |  | 1 Months Ended |  |  | 1 Months Ended |  | 1 Months Ended |  |
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Dec. 31, 2013 | Dec. 31, 2012 | Dec. 31, 2013 | Feb. 03, 2014 Subsequent Event | Feb. 07, 2014 Subsequent Event | Feb. 28, 2014 Subsequent Event | Dec. 31, 2013 Warrant | Dec. 31, 2013 Minimum Warrant | Dec. 31, 2013 Maximum Warrant | Dec. 31, 2013 Weighted Average Warrant | Dec. 31, 2013 Public Offering | Dec. 31, 2013 Public Offering Series A Convertible Preferred Stock | Dec. 31, 2013 Public Offering | Dec. 31, 2005 Common Stock | Dec. 31, 2004 Common Stock | Dec. 31, 2003 Common Stock | Feb. 03, 2014 Common Stock Subsequent Event | Dec. 31, 2013 Common Stock Public Offering | Dec. 31, 2013 Preferred Stock Public Offering | Aug. 02, 2012 2012 Equity Financings Registered Direct Offering | Aug. 02, 2012 2012 Equity Financings Registered Direct Offering Common Stock | Dec. 18, 2012 2012 Equity Financings PIPE Transaction | Oct. 22, 2012 2012 Equity Financings PIPE Transaction | Dec. 18, 2012 2012 Equity Financings PIPE Transaction Common Stock | Oct. 22, 2012 2012 Equity Financings PIPE Transaction Common Stock | Jan. 31, 2013 2013 Equity Financings Registered Direct Offering | Jan. 31, 2013 2013 Equity Financings Registered Direct Offering Common Stock | Jan. 22, 2013 2013 Equity Financings PIPE Transaction | Jan. 22, 2013 2013 Equity Financings PIPE Transaction Common Stock | Dec. 31, 2013 Director And Chief Executive Officer Public Offering
Equity financings and warrants (Textual) [Abstract] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Aggregate common stock sold | 15,685,562 | 2,660,315 | 15,685,562 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 406,099 |  | 86,186 | 137,530 |  |  | 164,636 |  | 356,430 |  |
Warrants available to purchase additional commons shares |  |  |  | 1,279,057 |  |  |  |  |  |  | 6,250,000 |  |  |  |  |  |  |  |  | 304,575 |  | 64,640 | 103,148 |  |  | 65,855 |  | 249,501 |  | 39,050
Aggregate gross proceeds |  |  |  | $ 8,700,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 953,000 |  | $ 250,000 | $ 325,000 |  |  | $ 730,000 |  | $ 1,000,000 |  |
Proceeds from the issuance of common stock | 1,741,000 | 1,528,000 | 15,850,000 |  | 7,900,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 741,000 |  | 230,000 | 280,000 |  |  | 616,000 |  | 805,000 |  |
Registered Direct Offering Close Date |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | Aug. 08, 2012 |  |  |  |  |  | Feb. 04, 2013 |  |  |  |
Purchase price for common stock unit |  |  |  | $ 1.70 |  |  |  |  |  |  |  | $ 160 |  |  |  |  |  |  |  | $ 2.35 |  | $ 2.90 | $ 2.36 |  |  | $ 4.43 |  | $ 2.81 |  |
Warrant coverage ratio |  |  |  |  |  |  |  |  |  |  |  |  | 50 |  |  |  | 0.25 |  |  |  | 0.75 |  |  | 0.75 | 0.75 |  | 0.40 |  | 0.70 |
Warrant price per share |  |  |  | 2.125 |  |  |  | 1.60 | 116.89 | 2.32 |  |  | 1.60 |  |  |  |  |  |  | 2.76 |  | 2.34 | 1.80 |  |  | 4.13 |  | 2.28 |  |
Public Equity Offering Close Date |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | Dec. 20, 2012 | Oct. 25, 2012 |  |  |  |  | Jan. 25, 2013 |  |
Warrants were exercisable upon issuance, expiry year |  |  |  | 5 years |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 7 years | 5 years |  |  | 5 years |  | 7 years |  |
Closing bid price of the common stock |  |  |  | 125.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 100.00% | 100.00% |  |  |  |  | 100.00% |  |
Shares issued |  |  |  |  |  |  |  |  |  |  | 125,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Aggregate gross proceeds |  |  |  |  |  |  |  |  |  |  |  | 20,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from the issuance of preferred stock | 20,000,000 |  | 52,316,000 |  |  |  |  |  |  |  | 17,900,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred Stock Purchased by Officer |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 781
Common stock shares issued upon conversion of each share of convertible preferred stock |  |  |  |  |  |  |  |  |  |  |  |  | 100 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock liquidation preference per share |  |  |  |  |  |  |  |  |  |  |  |  | $ 0.001 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of shares of preferred stock converted in to common stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 125,000 |  |  |  |  |  |  |  |  |  |  |
Number of shares of common stock issued in conversion of preferred stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 12,500,000 |  |  |  |  |  |  |  |  |  |  |  |
Number of warrants outstanding |  |  |  |  |  |  | 8,147,484 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Intrinsic value of embedded beneficial conversion feature | $ 2,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Aggregate common stock sold |  |  |  |  |  | 5,116,228 |  |  |  |  |  |  |  | 2,922 | 19,720 | 2,588 |  |  |  |  |  |  |  |  |  |  |  |  |  |

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