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Commitments and Contingencies (Details Textual) (USD $)
 1 Months Ended 12 Months Ended 144 Months Ended 12 Months Ended 12 Months Ended
Jul. 31, 2008
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2013
Dec. 31, 2013
Broomfield, Colorado
Jun. 30, 2011
Broomfield, Colorado
sqft
Aug. 08, 2008
Broomfield, Colorado
sqft
Dec. 31, 2013
Westminster, Colorado
Aug. 01, 2013
Westminster, Colorado
sqft
Commitments and Contingencies (Textual) [Abstract]                  
Area of office facilities taken on lease           4,500 15,000   5,300
Lease term         5 years     3 years  
Lease expiry period         2013-09     2016-09  
Milestone payment $ 500,000                
Expected milestone payments upon approval 8,000,000                
Another expected milestone payments upon approval 5,000,000                
Minimum percentage of royalty obligation 12.50%                
Maximum percentage of royalty obligation 25.00%                
Product sales levels royalty 5.00%                
Minimum percentage of range of royalties that can be buy down 12.50%                
Maximum percentage of range of royalties that can be buy down 17.00%                
Milestone payment due period 6 months                
Clinical research agreement with Duke University, termination notice period   90 days              
Rent expense   $ 63,000 $ 48,000 $ 578,000