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The Company and Summary of Significant Accounting Policies (Details) (USD $) | 1 Months Ended | 3 Months Ended | 12 Months Ended | 147 Months Ended | 1 Months Ended | 3 Months Ended
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Mar. 04, 2013 | Mar. 31, 2014 Patients | Mar. 31, 2013 | Dec. 31, 2013 | Mar. 31, 2014 | Mar. 31, 2014 | Feb. 28, 2014 Two Zero One Four Equity Financings Registered Direct Offering | Mar. 31, 2014 Phase 3 heart failure (HF) trial of Gencaro Patients
Company Development Stage and Basis of Presentation (Textual) [Abstract] |  |  |  |  |  |  |  |
Number of patients |  |  |  |  |  |  |  | 2,708
Number of patients company plans to enroll |  | 200 |  |  |  |  |  | 420
Number of years to complete the study |  | 2 years 6 months |  |  |  |  |  |
Loss from operations |  | $ (2,390,000) | $ (1,070,000) |  | $ (108,500,000) | $ (108,473,000) |  |
Cash flows from operations |  |  |  |  | (106,400,000) |  |  |
Fund raised through sale of convertible preferred and common stock |  |  |  | 19,300,000 |  | 10,841,000 |  |
Proceeds from the issuance of common stock |  | $ 9,018,000 | $ 1,741,000 |  |  | $ 24,868,000 | $ 7,900,000 |
Reverse stock split | 1-for-6 reverse split |  |  |  |  |  |  |

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