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Share- based Compensation | 3 Months Ended
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Mar. 31, 2014
Share-based Compensation | (8) Share-based Compensation For the three month period ended March 31, 2014 and 2013 and for the period from Inception through March 31, 2014, the Company recognized the following non-cash, share-based compensation expense in the consolidated statement of operations (in thousands):
| Three Months Ended March 31, |  |  | Period from December 17, 2001 (date of inception) to March 31, |
| 2014 |  |  | 2013 |  |  | 2014 |
Research and Development | $ | 40 |  |  | $ | 15 |  |  | $ | 707 |
Selling, General and Administrative |  | 118 |  |  |  | 27 |  |  |  | 1,935 |
Restructuring Expense |  | — |  |  |  | — |  |  |  | 387 |
Total | $ | 158 |  |  | $ | 42 |  |  | $ | 3,029 |
Stock option and stock award transactions for the three month period ended March 31, 2014 under the Company’s stock incentive plans were as follows:
| Number of Options |  |  | Weighted Average Exercise Price |  |  | Weighted Average Remaining Contractual Term (in years) |
Options outstanding at December 31, 2013 |  | 843,442 |  |  | $ | 3.76 |  |  |  | 8.94 |
Granted |  | 200,079 |  |  |  | 1.91 |  |  |  |  |
Exercised | — |  |  | — |  |  |  |  |
Forfeited and cancelled |  | (27 | ) |  |  | 1,908.00 |  |  |  |  |
Options outstanding at March 31, 2014 |  | 1,043,494 |  |  | $ | 3.35 |  |  |  | 8.93 |
Options exercisable at March 31, 2014 |  | 266,655 |  |  | $ | 8.42 |  |  |  | 7.13 |
Options vested and expected to vest |  | 1,031,382 |  |  | $ | 3.37 |  |  |  | 8.92 |
| Number of Shares |  |  | Weighted Average Grant Date Fair Value |
Restricted stock units outstanding at December 31, 2013 |  | 419,000 |  |  | $ | 1.39 |
Granted |  | 191,700 |  |  |  | 1.95 |
Vested and released | — |  |  | — |
Forfeited and cancelled | — |  |  | — |
Restricted stock units outstanding at March 31, 2014 |  | 610,700 |  |  | $ | 1.57 |

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- Definition The entire disclosure for compensation-related costs for equity-based compensation, which may include disclosure of policies, compensation plan details, allocation of equity compensation, incentive distributions, equity-based arrangements to obtain goods and services, deferred compensation arrangements, employee stock ownership plan details and employee stock purchase plan details. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 50 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6406099&loc=d3e25284-112666 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 40 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6418621&loc=d3e17540-113929 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 4 -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5444-113901 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Staff Accounting Bulletin (SAB) -Number Topic 14 + Details
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