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Merger with Nuvelo, Inc. on January 27, 2009 (Details) (USD $)
 1 Months Ended 147 Months Ended
Jan. 27, 2009
Mar. 31, 2014
Business Acquisition [Line Items]    
Estimated total acquisition consideration $ 11,900,000  
Net assets acquired in the Merger 37,200,000  
Net assets acquired, including cash, cash equivalents and marketable securities 45,500,000  
Gain on bargain purchase $ 25,300,000 $ 25,282,000