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The Company and Summary of Significant Accounting Policies (Details Textual) |  |  | 12 Months Ended
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Jun. 16, 2015 USD ($) | Feb. 07, 2014 USD ($) | Dec. 31, 2016 Patients | Dec. 31, 2015 USD ($) Patients Segment
Company And Summary Of Significant Accounting Policies Table [Line Items] |  |  |  |
Date of completion of business combination with Nuvelo |  |  |  | Jan. 27, 2009
Revenues |  |  |  | $ 0
Description of reverse stock split |  |  |  | 1-for-7 reverse split
Reverse stock split |  |  |  | 0.143
Concentrations of credit risk |  |  |  | $ 0
Number of segments | Segment |  |  |  | 1
Registered Direct Offering |  |  |  |
Company And Summary Of Significant Accounting Policies Table [Line Items] |  |  |  |
Proceeds from the issuance of security units |  | $ 7,900,000 |  |
Private Investment In Public Entity Transaction |  |  |  |
Company And Summary Of Significant Accounting Policies Table [Line Items] |  |  |  |
Proceeds from the issuance of security units | $ 34,200,000 |  |  |
Phase 3 heart failure (HF) trial of Gencaro | BEST Trial |  |  |  |
Company And Summary Of Significant Accounting Policies Table [Line Items] |  |  |  |
Number of patients | Patients |  |  |  | 2,708
Phase 2B/Phase 3 | GENETIC-AF Trial |  |  |  |
Company And Summary Of Significant Accounting Policies Table [Line Items] |  |  |  |
Number of patients company plans to enroll | Patients |  |  |  | 620
Trial endpoint, term |  |  |  | 168 days
Phase 2B | GENETIC-AF Trial | Forecast | Minimum |  |  |  |
Company And Summary Of Significant Accounting Policies Table [Line Items] |  |  |  |
Number of patients company plans to enroll | Patients |  |  | 150 |

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