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Share-based Compensation - Summary of Stock Option Activities (Details) - $ / shares
 3 Months Ended 12 Months Ended
Mar. 31, 2016
Dec. 31, 2015
Number of Stock Options    
Options outstanding beginning of period 161,278  
Number of Options, Granted 32,000  
Number of Options, Forfeited and cancelled (18,237)  
Options outstanding end of the period 175,041 161,278
Options exercisable, end of period, Number of Options 114,852  
Options vested and expected to vest, Number of Options 174,914  
Stock Options, Weighted Average Exercise Price    
Weighted Average exercise Price, Options Outstanding, Beginning of period $ 18.30  
Weighted average exercise price, Granted 3.44  
Weighted average exercise price, Forfeited and cancelled 28.94  
Weighted Average exercise Price, Options Outstanding, end of period 14.48 $ 18.30
Weighted average exercise price, Options exercisable, end of period 17.94  
Weighted Average exercise Price, Options vested and expected to vest, end of period $ 14.48  
Stock Options, Weighted Average Remaining Contractual Term    
Weighted Average Remaining Contractual Term (in years) Options Outstanding 7 years 11 months 5 days 6 years 11 months 19 days
Options exercisable, Weighted Average Remaining Contractual Term (in years) 7 years 5 months 27 days  
Options vested and expected to vest, Weighted Average Remaining Contractual Term (in years) 7 years 11 months 5 days