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STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Cash flows from operating activities:    
Net loss $ (12,200) $ (8,277)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 17 14
Amortization of other assets 207 133
Amortization of premiums and discounts on marketable securities 100  
Share-based compensation 605 454
Change in operating assets and liabilities:    
Other current assets (98) 147
Other assets (303) (229)
Accounts payable 648 (167)
Accrued compensation and employee benefits (507) (215)
Accrued expenses and other liabilities 391 229
Other (5) (3)
Net cash used in operating activities (11,145) (7,914)
Cash flows from investing activities:    
Purchases of property and equipment (8) (9)
Purchases of marketable securities (20,504)  
Proceeds from maturities of marketable securities 950  
Net cash used in investing activities (19,562) (9)
Cash flows from financing activities:    
Proceeds from the issuance of common stock   37,000
Common stock offering costs   (2,756)
Repayment of principal on vendor finance agreement   (193)
Net cash provided by financing activities   34,051
Net (decrease) increase in cash and cash equivalents (30,707) 26,128
Cash and cash equivalents, beginning of period 38,802 15,354
Cash and cash equivalents, end of period 8,095 41,482
Supplemental cash flow information:    
Interest paid   4
Supplemental disclosure of noncash investing and financing transactions:    
Common stock offering costs accrued but not yet paid (11) $ 69
Change in unrealized loss on marketable securities (6)  
Leasehold improvement lease incentive $ 48