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Share-based Compensation (Details Textual) - USD ($)
1 Months Ended 12 Months Ended
Jun. 30, 2016
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Number of shares outstanding under Equity plan   629,629 161,278 152,584
Stock options award, expiration   10 years    
Weighted Average exercise Price of Options Outstanding   $ 6.30 $ 18.30 $ 20.20
Total intrinsic value of options exercised   $ 0 $ 0  
Stock-based compensation expense related to non-employees     $ 25,000  
Employee Stock Option        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Unrecognized compensation expense related to unvested options   $ 932,000    
Maturity period of weighted average period of compensation expenses   1 year 3 months 18 days    
Restricted Stock Units (RSUs)        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Maturity period of weighted average period of compensation expenses   1 year 2 months 12 days    
Unrecognized compensation cost related to unvested stock awards   $ 143,000    
Minimum        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Stock options award, vesting period   3 years    
Percentage holding for stock options exercise price   10.00%    
Minimum | Incentive Stock Option        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Percentage of exercise price of stock option   100.00%    
Minimum | Incentive Stock Option | Stockholders        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Percentage of exercise price of stock option   110.00%    
Minimum | Restricted Stock Units (RSUs)        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Restricted Stock Units award, requisite service period   3 years    
Maximum        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Stock options award, vesting period   4 years    
Maximum | Restricted Stock Units (RSUs)        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Restricted Stock Units award, requisite service period   4 years    
2013 Plan        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Increase in number of shares reserve for issuance under amended Equity Plan 1,000,000      
Number of shares issuable under Equity plan 1,321,428      
Number of shares outstanding under Equity plan   651,227    
Shares reserved for future   592,430    
Options and awards granted   487,700 52,801  
Two Thousand And Four Stock Option Plan        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Number of shares outstanding under Equity plan   5,643    
Weighted Average exercise Price of Options Outstanding   $ 102.64    
Other Stock Option Plan        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Number of shares outstanding under Equity plan   3,498    
Weighted Average exercise Price of Options Outstanding   $ 157.35