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STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Cash flows from operating activities:    
Net loss $ (16,444) $ (11,445)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 24 19
Amortization of other assets 296 189
Amortization of premiums and discounts on marketable securities 161  
Share-based compensation 576 599
Change in operating assets and liabilities:    
Other current assets (47) 213
Other assets (432) (211)
Accounts payable 841 (431)
Accrued compensation and employee benefits 50 340
Accrued expenses and other liabilities (3) 196
Other (9) (3)
Net cash used in operating activities (14,987) (10,534)
Cash flows from investing activities:    
Purchase of property and equipment (12) (11)
Purchases of marketable securities (20,504)  
Proceeds from maturities of marketable securities 4,102  
Net cash used in investing activities (16,414) (11)
Cash flows from financing activities:    
Proceeds from the issuance of common stock   37,000
Common stock offering costs   (2,814)
Repayment of principal on vendor finance agreement   (193)
Net cash provided by financing activities   33,993
Net (decrease) increase in cash and cash equivalents (31,401) 23,448
Cash and cash equivalents, beginning of period 38,802 15,354
Cash and cash equivalents, end of period 7,401 38,802
Supplemental cash flow information:    
Interest paid   4
Supplemental disclosure of noncash investing and financing transactions:    
Common stock offering costs accrued but not yet paid (11) $ 11
Change in unrealized loss on marketable securities (19)  
Leasehold improvement lease incentive $ 48