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STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Cash flows from operating activities:    
Net loss $ (9,860) $ (7,541)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 14 9
Amortization of other assets 179 117
Amortization of premiums and discounts on marketable securities 91 38
Share-based compensation 220 338
Change in operating assets and liabilities:    
Other current assets 102 (263)
Other assets   (303)
Accounts payable (141) 391
Accrued compensation and employee benefits (578) (569)
Accrued expenses and other liabilities 671 375
Other   (1)
Net cash used in operating activities (9,302) (7,409)
Cash flows from investing activities:    
Purchases of property and equipment (2) (2)
Purchases of marketable securities (2,039) (17,462)
Proceeds from maturities of marketable securities 11,150 450
Net cash provided by (used in) investing activities 9,109 (17,014)
Cash flows from financing activities:    
Proceeds from the issuance of common stock 2,284  
Common stock offering costs (221)  
Repayment of principal on vendor finance agreement (170)  
Net cash provided by financing activities 1,893  
Net increase (decrease) in cash and cash equivalents 1,700 (24,423)
Cash and cash equivalents, beginning of period 7,401 38,802
Cash and cash equivalents, end of period 9,101 14,379
Supplemental cash flow information:    
Interest paid 4  
Supplemental disclosure of noncash investing and financing transactions:    
Vendor finance agreement 86  
Proceeds receivable from the issuance of common stock (198)  
Common stock offering costs accrued but not yet paid 82 (11)
Change in unrealized loss on marketable securities $ 14 13
Leasehold improvement lease incentive   $ 48