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STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Cash flows from operating activities:    
Net loss $ (14,293) $ (12,200)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 21 17
Amortization of other assets 269 207
Amortization of premiums and discounts on marketable securities 109 100
Share-based compensation 339 605
Change in operating assets and liabilities:    
Other current assets 186 (98)
Other assets   (303)
Accounts payable 29 648
Accrued compensation and employee benefits (526) (507)
Accrued expenses and other liabilities 590 391
Other   (5)
Net cash used in operating activities (13,276) (11,145)
Cash flows from investing activities:    
Purchases of property and equipment (2) (8)
Purchases of marketable securities (5,471) (20,504)
Proceeds from maturities of marketable securities 13,650 950
Net cash provided by (used in) investing activities 8,177 (19,562)
Cash flows from financing activities:    
Proceeds from the issuance of common stock 6,515  
Common stock offering costs (419)  
Repayment of principal on vendor finance agreement (256)  
Net cash provided by financing activities 5,840  
Net increase (decrease) in cash and cash equivalents 741 (30,707)
Cash and cash equivalents, beginning of period 7,401 38,802
Cash and cash equivalents, end of period 8,142 8,095
Supplemental cash flow information:    
Interest paid 6  
Supplemental disclosure of noncash investing and financing transactions:    
Common stock offering costs accrued but not yet paid   (11)
Change in unrealized loss on marketable securities $ 16 (6)
Leasehold improvement lease incentive   $ 48