Share-based Compensation (Tables)

9 Months Ended

Sep. 30, 2017

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

Summary of Non-cash, Share-based Compensation Expense

For the three and nine month periods ended September 30, 2017 and 2016, the Company recognized the following non-cash, share-based compensation expense in the statements of operations (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2017		2016		2017		2016
Research and development	$	44	$	94	$	124	$	189
General and administrative		75		173		215		416
Total	$	119	$	267	$	339	$	605

Summary of Stock Option Activities

Stock option transactions for the nine month period ended September 30, 2017 under the Company’s stock incentive plans were as follows:

	Number of Options			Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (in years)
Options outstanding at December 31, 2016		629,629		$	6.30		8.86
Granted		469,600			2.54
Exercised	—			—
Forfeited and cancelled		(278,642	)		3.38
Options outstanding at September 30, 2017		820,587		$	5.14		8.65
Options exercisable at September 30, 2017		294,215		$	9.27		7.59
Options vested and expected to vest		819,477		$	5.14		8.64

Summary of RSU Activity

Stock award transactions related to restricted stock units for the nine month period ended September 30, 2017 under the Company’s stock incentive plans were as follows:

	Number of Shares			Weighted Average Grant Date Fair Value
Restricted stock units outstanding at December 31, 2016		30,739		$	7.91
Granted		—			—
Vested and released		(14,938	)		7.98
Forfeited and cancelled		(400	)		6.03
Restricted stock units outstanding at September 30, 2017		15,401		$	7.90