Company and summary of significant accounting policies.

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The cash inflow associated with the amount received from entity's raising of capital via registered direct offering, net of related financing costs.

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Number of patients enrolled.

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- Definition

Date when the acquirer obtains control of the acquiree, in CCYY-MM-DD format.

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 805
-SubTopic 10
-Section 25
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- Definition

Amount of cash outflow for realized tax benefit related to deductible compensation cost reported on the entity's tax return for equity instruments in excess of the compensation cost for those instruments recognized for financial reporting purposes.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
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-Section 55
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The fair value of financial assets, which are not recognized in the financial statements (off-balance sheet) because they fail to meet some other criterion for recognition.

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-Section 50
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- Definition

Number of operating segments. An operating segment is a component of an enterprise: (a) that engages in business activities from which it may earn revenues and incur expenses (including revenues and expenses relating to transactions with other components of the same enterprise), (b) whose operating results are regularly reviewed by the enterprise's chief operating decision maker to make decisions about resources to be allocated to the segment and assess its performance, and (c) for which discrete financial information is available. An operating segment may engage in business activities for which it has yet to earn revenues, for example, start-up operations may be operating segments before earning revenues.

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Amount of revenue recognized from goods sold, services rendered, insurance premiums, or other activities that constitute an earning process. Includes, but is not limited to, investment and interest income before deduction of interest expense when recognized as a component of revenue, and sales and trading gain (loss).

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-Publisher FASB
-Name Accounting Standards Codification
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-Section S99
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For net-share settlement of share-based awards when the employer settles employees' income tax withholding obligations, this element represents the number of shares the employees use to repay the employer.

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The Company and Summary of Significant Accounting Policies (Details Textual)	1 Months Ended	12 Months Ended
	Jan. 19, 2018 USD ($)	Dec. 31, 2017 USD ($) Patients Segment	Dec. 31, 2016 USD ($) shares
Company And Summary Of Significant Accounting Policies Table [Line Items]
Date of completion of business combination with Nuvelo		Jan. 27, 2009
Revenues		$ 0
Excess tax benefits from share-based payments			$ 0
Number of shares withhold to satisfy statutory income tax withholding obligations \| shares			0
Concentrations of credit risk		$ 0
Number of segments \| Segment		1
At the Market Offering under Sales Agreement \| Subsequent Event
Company And Summary Of Significant Accounting Policies Table [Line Items]
Net proceeds from issuance of common stock	$ 3,400,000
Phase 2B \| GENETIC-AF Trial
Company And Summary Of Significant Accounting Policies Table [Line Items]
Number of patients enrolled \| Patients		267