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STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Costs and expenses:    
Research and development $ 14,076,000 $ 12,348,000
General and administrative 4,636,000 4,265,000
Total costs and expenses 18,712,000 16,613,000
Loss from operations (18,712,000) (16,613,000)
Interest and other income 167,000 169,000
Interest expense (6,000)  
Loss before income taxes (18,551,000) (16,444,000)
Income tax benefit 61,000 0
Net loss (18,490,000) (16,444,000)
Change in unrealized loss on marketable securities 17,000 (19,000)
Comprehensive loss $ (18,473,000) $ (16,463,000)
Net loss per share:    
Basic and diluted $ (1.77) $ (1.81)
Weighted average shares outstanding:    
Basic and diluted 10,431,391 9,067,438