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STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Cash flows from operating activities:    
Net loss $ (18,490) $ (16,444)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 27 24
Amortization of other assets 329 296
Amortization of premiums and discounts on marketable securities 119 161
Share-based compensation 458 576
Change in operating assets and liabilities:    
Other current assets 437 (47)
Other assets   (432)
Accounts payable (583) 841
Accrued compensation and employee benefits 38 50
Accrued expenses and other liabilities 193 (3)
Other   (9)
Net cash used in operating activities (17,472) (14,987)
Cash flows from investing activities:    
Purchase of property and equipment (3) (12)
Purchases of marketable securities (5,471) (20,504)
Proceeds from maturities of marketable securities 18,400 4,102
Net cash provided by (used in) investing activities 12,926 (16,414)
Cash flows from financing activities:    
Proceeds from the issuance of common stock 6,551  
Common stock offering costs (448)  
Repayment of principal on vendor finance agreement (256)  
Net cash provided by financing activities 5,847  
Net increase (decrease) in cash and cash equivalents 1,301 (31,401)
Cash and cash equivalents, beginning of year 7,401 38,802
Cash and cash equivalents, end of year 8,702 7,401
Supplemental cash flow information:    
Interest paid 6  
Income tax refund received 38  
Supplemental disclosure of noncash investing and financing transactions:    
Common stock offering costs accrued but not yet paid 7 (11)
Change in unrealized loss on marketable securities $ 17 (19)
Leasehold improvement lease incentive   $ 48