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STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2018 | Dec. 31, 2017
Cash flows from operating activities: |  |
Net loss | $ (7,933) | $ (18,490)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation | 22 | 27
Amortization of other assets |  | 329
Amortization of premiums and discounts on marketable securities | 2 | 119
Share-based compensation | 273 | 458
Change in operating assets and liabilities: |  |
Other current assets | 689 | 437
Accounts payable | (392) | (583)
Accrued compensation and employee benefits | (607) | 38
Accrued expenses and other liabilities | (298) | 193
Net cash used in operating activities | (8,244) | (17,472)
Cash flows from investing activities: |  |
Purchase of property and equipment | (4) | (3)
Purchases of marketable securities |  | (5,471)
Proceeds from maturities of marketable securities | 3,050 | 18,400
Net cash provided by investing activities | 3,046 | 12,926
Cash flows from financing activities: |  |
Proceeds from the issuance of common stock | 3,532 | 6,551
Common stock offering costs | (117) | (448)
Repayment of principal on vendor finance agreement | (311) | (256)
Net cash provided by financing activities | 3,104 | 5,847
Net (decrease) increase in cash and cash equivalents | (2,094) | 1,301
Cash and cash equivalents, beginning of year | 8,702 | 7,401
Cash and cash equivalents, end of year | 6,608 | 8,702
Supplemental cash flow information: |  |
Interest paid | 8 | 6
Income tax refund received | 54 | 38
Supplemental disclosure of noncash investing and financing transactions: |  |
Common stock offering costs accrued but not yet paid |  | 7
Change in unrealized loss on marketable securities | $ 2 | $ 17

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