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Income Taxes (Details Textual) - USD ($)
 12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Income Tax [Line Items]      
Net operating loss carryforwards   $ 170,300,000  
Tax Credit Carryforward, Description The net operating loss carryforwards beginning in 2018, have no expiration, but are limited to 80% of taxable income.    
Percentage limited to taxable income on operating loss carryforward 80.00%    
Valuation allowance $ 44,627,000 $ 43,529,000  
Increase net deferred tax asset $ 1,100,000    
Federal statutory income tax rate 21.00% 21.00%  
Reserve for uncertain tax positions $ 0 $ 0  
Interest or penalties recognized $ 0 0  
Open tax year 2009    
Research Tax Credit Carryforward      
Income Tax [Line Items]      
Research and experimentation credits   $ 1,700,000  
Operating loss carryforwards, limitations on use Utilization of net operating losses and tax credits, including those acquired as a result of the Merger, will be subject to an annual limitation due to ownership change limitations provided by Internal Revenue Code Section 382. The Company believes that an ownership change limitation as defined under Section 382 of the U.S. Internal Revenue Code occurred as a result of its various historical financing transactions, including its offering of common stock completed in June 2015. Future utilization of the federal net operating losses and tax credit carryforwards accumulated from June 2005 to the change in ownership date will be subject to annual limitations to offset future taxable income. The annual limitation may result in the expiration of the net operating losses and credits before utilization. As such, a portion of the Company’s net operating loss carryforwards may be limited    
Tax credit carryforward, limitations on use Utilization of net operating losses and tax credits, including those acquired as a result of the Merger, will be subject to an annual limitation due to ownership change limitations provided by Internal Revenue Code Section 382. The Company believes that an ownership change limitation as defined under Section 382 of the U.S. Internal Revenue Code occurred as a result of its various historical financing transactions, including its offering of common stock completed in June 2015. Future utilization of the federal net operating losses and tax credit carryforwards accumulated from June 2005 to the change in ownership date will be subject to annual limitations to offset future taxable income. The annual limitation may result in the expiration of the net operating losses and credits before utilization. As such, a portion of the Company’s net operating loss carryforwards may be limited    
Earliest Tax Year      
Income Tax [Line Items]      
Operating loss carryforwards expiration year     2025
Latest Tax Year      
Income Tax [Line Items]      
Operating loss carryforwards expiration year     2037