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Share-based Compensation - Summary of Stock Option Activities (Details) - $ / shares
9 Months Ended 12 Months Ended
Sep. 30, 2020
Dec. 31, 2019
Number of Stock Options    
Number of Options, Options outstanding, beginning of period 31,136  
Number of Options, Granted 6,250  
Number of Options, Forfeited and cancelled (248)  
Number of Options, Options outstanding, end of period 37,138 31,136
Number of Options, Options exercisable, end of period 31,013  
Number of Options, Options vested and expected to vest 37,138  
Stock Options, Weighted Average Exercise Price    
Weighted Average Exercise Price, Options outstanding, beginning of period $ 84.50  
Weighted Average Exercise Price, Granted 5.96  
Weighted Average Exercise Price, Forfeited and cancelled 610.46  
Weighted Average Exercise Price, Options outstanding, end of period 67.77 $ 84.50
Weighted Average Exercise Price, Options exercisable, end of period 80.37  
Weighted Average Exercise Price, Options vested and expected to vest, end of period $ 67.77  
Stock Options, Weighted Average Remaining Contractual Term    
Weighted Average Remaining Contractual Term (in years), Options outstanding 6 years 3 months 14 days 6 years 3 months 3 days
Weighted Average Remaining Contractual Term (in years), Options exercisable 5 years 6 months 29 days  
Weighted Average Remaining Contractual Term (in years), Options vested and expected to vest 6 years 3 months 14 days