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Equity Financings and Warrants (Details Textual) - USD ($)
$ / shares in Units, $ in Thousands
9 Months Ended 12 Months Ended
Jun. 03, 2020
Sep. 30, 2021
Sep. 30, 2020
Dec. 31, 2020
Apr. 30, 2021
Jul. 22, 2020
Jul. 14, 2020
Jan. 11, 2017
Equity Financing And Warrants [Line Items]                
Net proceeds from issuance of common stock   $ 24,070 $ 49,644          
Common stock, par value   $ 0.001   $ 0.001        
Common stock, shares issued   14,410,143   9,548,150        
JonesTrading                
Equity Financing And Warrants [Line Items]                
Percentage of selling commission per additional shares sold               3.00%
Sales Agreement                
Equity Financing And Warrants [Line Items]                
Common stock, shares issued       2,214,301        
Net proceeds from issuance of common stock       $ 14,400        
Sales Agreement | JonesTrading                
Equity Financing And Warrants [Line Items]                
Common stock, par value               $ 0.001
Aggregate offering price of common stock authorized             $ 32,400 $ 7,300
2020 Sales Agreement                
Equity Financing And Warrants [Line Items]                
Net proceeds from issuance of common stock   $ 23,300   $ 28,900        
Aggregate offering price of common stock authorized         $ 50,000 $ 54,000    
Sale of common stock   4,861,993   5,066,279        
Direct Offering                
Equity Financing And Warrants [Line Items]                
Common stock issued 348,000              
Purchase price per share $ 9.00              
Pre-funded warrants to purchase shares of common stock 325,500              
Purchase price per warrant $ 8.999              
Net proceeds from issuance of common stock $ 5,300              
Percentage of selling commission per additional shares sold 8.00%