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Equity Financings and Warrants (Details Textual) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Jul. 22, 2020
Equity Financing And Warrants [Line Items]        
Common stock, par value $ 0.001   $ 0.001  
Net proceeds from issuance of common stock   $ 24,070    
JonesTrading        
Equity Financing And Warrants [Line Items]        
Percentage of selling commission per additional shares sold       3.00%
Sales Agreement | JonesTrading        
Equity Financing And Warrants [Line Items]        
Common stock, par value       $ 0.001
Aggregate offering price of common stock authorized       $ 54,000
2020 Sales Agreement        
Equity Financing And Warrants [Line Items]        
Sale of common stock 0   4,861,993  
Net proceeds from issuance of common stock     $ 23,300