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Commitments and Contingencies (Details Textual)
€ in Millions
1 Months Ended 3 Months Ended 12 Months Ended
Nov. 30, 2023
Jul. 31, 2021
EUR (€)
Jun. 30, 2021
ft²
Mar. 31, 2024
USD ($)
Mar. 31, 2023
USD ($)
Dec. 31, 2023
USD ($)
Apr. 20, 2024
USD ($)
Dec. 31, 2022
USD ($)
Aug. 29, 2020
ft²
Commitments And Contingencies [Line Items]                  
Amount of retention bonuses       $ 311,000          
Percentage of retention bonuses 50.00%                
Retention bonus paid           $ 86,000      
Restructuring Reserve, Current           0      
Severance expense           $ 159,000      
Area of office facilities taken on lease | ft²                 5,200
Operating lease term                 42 months
Additional operating lease term       6 months          
Lease renewal option       extend the lease term six (6) months through September 2024          
Operating lease extended expiry       2024-09          
Percentage of base rent to be paid monthly       125.00%          
Lessee, Operating Lease, Existence of Option to Extend [true false]       true          
Area of additional office facilities taken on sublease | ft²     3,000            
Operating sublease term     29 months            
Lessee, operating lease, assumptions and judgments, allocation of lease and nonlease component       The leases include real estate taxes and insurance, which is not a lease component and is not included in the lease obligation. In addition, common area maintenance charges are based on actual costs incurred and are a non-lease component that is not included in the lease obligation.          
Operating lease, cash paid for measurement of lease liabilities       $ 23,000 $ 33,000        
Lease liability       $ 48,000          
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]       Accrued expenses and other liabilities          
Weighted-average remaining lease term       6 months          
Weighted-average discount rate       7.00%          
Subsequent Event                  
Commitments And Contingencies [Line Items]                  
Amount of retention bonuses             $ 444,000    
General and Administrative Expense                  
Commitments And Contingencies [Line Items]                  
Rent expense       $ 22,000 $ 31,000        
Research and development | Patent Assignment Agreement | University Medical Center of Johannes Gutenberg University Mainz                  
Commitments And Contingencies [Line Items]                  
Potential upfront and milestone obligations and royalty obligations | €   € 1.6              
Clinical development decisions                  
Commitments And Contingencies [Line Items]                  
Amount of retention bonuses               $ 265,000