    <SEC-DOCUMENT>0001140361-24-043698-index.html : 20241018
    <SEC-HEADER>0001140361-24-043698.hdr.sgml : 20241018
    <ACCEPTANCE-DATETIME>20241018161103
    ACCESSION NUMBER:		0001140361-24-043698
    CONFORMED SUBMISSION TYPE:	DEF 14A
    PUBLIC DOCUMENT COUNT:		4
    CONFORMED PERIOD OF REPORT:	20241114
    FILED AS OF DATE:		20241018
    DATE AS OF CHANGE:		20241018

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Oruka Therapeutics, Inc.
    		CENTRAL INDEX KEY:			0000907654
    		STANDARD INDUSTRIAL CLASSIFICATION:	IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
    		ORGANIZATION NAME:           	03 Life Sciences
    		IRS NUMBER:				363855489
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEF 14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	000-22873
    		FILM NUMBER:		241380856

    	BUSINESS ADDRESS:
    		STREET 1:		855 OAK GROVE AVE.
    		STREET 2:		SUITE 100
    		CITY:			MENLO PARK
    		STATE:			CA
    		ZIP:			94025
    		BUSINESS PHONE:		650-606-7910

    	MAIL ADDRESS:
    		STREET 1:		855 OAK GROVE AVE.
    		STREET 2:		SUITE 100
    		CITY:			MENLO PARK
    		STATE:			CA
    		ZIP:			94025

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	ARCA biopharma, Inc.
    		DATE OF NAME CHANGE:	20090128

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	NUVELO INC
    		DATE OF NAME CHANGE:	20030203

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	HYSEQ INC
    		DATE OF NAME CHANGE:	19970610
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEF 14A
    <SEQUENCE>1
    <FILENAME>ny20036093x2_def14a.htm
    <DESCRIPTION>DEF 14A
    <TEXT>
    Document 1 - file: ny20036093x2_def14a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>logo_oruka.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: logo_oruka.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>ny20036093x2_pc01.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: ny20036093x2_pc01.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>ny20036093x2_pc02.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: ny20036093x2_pc02.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>