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    ACCESSION NUMBER:		0001013762-24-000530
    CONFORMED SUBMISSION TYPE:	S-4/A
    PUBLIC DOCUMENT COUNT:		86
    FILED AS OF DATE:		20240722
    DATE AS OF CHANGE:		20240722

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			ARCA biopharma, Inc.
    		CENTRAL INDEX KEY:			0000907654
    		STANDARD INDUSTRIAL CLASSIFICATION:	IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
    		ORGANIZATION NAME:           	03 Life Sciences
    		IRS NUMBER:				363855489
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		S-4/A
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-279387
    		FILM NUMBER:		241132294

    	BUSINESS ADDRESS:
    		STREET 1:		10170 CHURCH RANCH WAY
    		STREET 2:		SUITE 100
    		CITY:			WESTMINSTER
    		STATE:			CO
    		ZIP:			80021
    		BUSINESS PHONE:		7209402200

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    		STREET 1:		10170 CHURCH RANCH WAY
    		STREET 2:		SUITE 100
    		CITY:			WESTMINSTER
    		STATE:			CO
    		ZIP:			80021

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	NUVELO INC
    		DATE OF NAME CHANGE:	20030203

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	HYSEQ INC
    		DATE OF NAME CHANGE:	19970610
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    <TYPE>EX-5.1
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