    <SEC-DOCUMENT>0001213900-25-033326-index.html : 20250418
    <SEC-HEADER>0001213900-25-033326.hdr.sgml : 20250418
    <ACCEPTANCE-DATETIME>20250418151013
    ACCESSION NUMBER:		0001213900-25-033326
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20241231
    FILED AS OF DATE:		20250418
    DATE AS OF CHANGE:		20250418
    EFFECTIVENESS DATE:		20250418

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Oruka Therapeutics, Inc.
    		CENTRAL INDEX KEY:			0000907654
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				363855489
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	000-22873
    		FILM NUMBER:		25850281

    	BUSINESS ADDRESS:
    		STREET 1:		855 OAK GROVE AVE.
    		STREET 2:		SUITE 100
    		CITY:			MENLO PARK
    		STATE:			CA
    		ZIP:			94025
    		BUSINESS PHONE:		650-606-7910

    	MAIL ADDRESS:
    		STREET 1:		855 OAK GROVE AVE.
    		STREET 2:		SUITE 100
    		CITY:			MENLO PARK
    		STATE:			CA
    		ZIP:			94025

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	ARCA biopharma, Inc.
    		DATE OF NAME CHANGE:	20090128

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	NUVELO INC
    		DATE OF NAME CHANGE:	20030203

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	HYSEQ INC
    		DATE OF NAME CHANGE:	19970610
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>ea0237916-03.pdf
    <DESCRIPTION>ANNUAL REPORT
    <TEXT>
    Document 1 - file: ea0237916-03.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>