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Condensed Consolidated Statements of Convertible Preferred Stock and Stockholders’ Equity (Deficit) (Unaudited) - USD ($) $ in Thousands | Convertible Preferred Stock Series B Non-Voting | Convertible Preferred Stock Series A | Convertible Preferred Stock Series A Non-Voting | Common Stock | Additional Paid-in Capital | Accumulated Other Comprehensive Gain (Loss) | Accumulated Deficit | Total
--- | --- | --- | --- | --- | --- | --- | --- | ---
Balance at Feb. 06, 2024 |  |  |  | $ 3 | $ (2) |  |  | $ 1
Balance (in Shares) at Feb. 06, 2024 |  |  |  | 3,197,975 |  |  |  |
Issuance of common stock |  |  |  | $ 2 | (2) |  |  |
Issuance of common stock (in Shares) |  |  |  | 2,207,553 |  |  |  |
Issuance of Series A convertible preferred stock, net of issuance costs of $69 |  | $ 2,931 |  |  |  |  |  |
Issuance of Series A convertible preferred stock, net of issuance costs of $69 (in Shares) |  | 20,000,000 |  |  |  |  |  |
Stock-based compensation expense |  |  |  |  | 17 |  |  | 17
Net loss |  |  |  |  |  |  | (7,077) | (7,077)
Balance at Mar. 31, 2024 |  | $ 2,931 |  | $ 5 | 13 |  | (7,077) | (7,059)
Balance (in Shares) at Mar. 31, 2024 |  | 20,000,000 |  | 5,405,528 |  |  |  |
Stock-based compensation expense |  |  |  |  | 321 |  |  | 321
Net loss |  |  |  |  |  |  | (22,243) | (22,243)
Balance at Jun. 30, 2024 |  | $ 2,931 |  | $ 5 | 334 |  | (29,320) | (28,981)
Balance (in Shares) at Jun. 30, 2024 |  | 20,000,000 |  | 5,405,528 |  |  |  |
Exchange of Series A convertible preferred stock for Series B non-voting convertible preferred stock upon the closing of the reverse recapitalization | $ 2,931 | $ (2,931) |  |  |  |  |  | 2,931
Exchange of Series A convertible preferred stock for Series B non-voting convertible preferred stock upon the closing of the reverse recapitalization (in Shares) | 137,138 | (20,000,000) |  |  |  |  |  |
Conversion of convertible notes (including accrued interest) into common stock upon the closing of the reverse recapitalization |  |  |  | $ 3 | 26,445 |  |  | 26,448
Conversion of convertible notes (including accrued interest) into common stock upon the closing of the reverse recapitalization (in Shares) |  |  |  | 2,722,207 |  |  |  |
Issuance of common stock and pre-funded warrants in the Pre-Closing Financing, |  |  |  | $ 20 | 248,437 |  |  | 248,457
Issuance of common stock and pre-funded warrants in the Pre-Closing Financing, (in Shares) |  |  |  | 20,061,932 |  |  |  |
Issuance costs of Pre-Closing Financing and reverse recapitalization |  |  |  |  | (20,480) |  |  | (20,480)
Issuance of common stock to former stockholders of ARCA biopharma, Inc. in connection with the closing of the reverse recapitalization |  |  |  | $ 1 | 4,999 |  |  | 5,000
Issuance of common stock to former stockholders of ARCA biopharma, Inc. in connection with the closing of the reverse recapitalization (in Shares) |  |  |  | 1,208,883 |  |  |  |
Issuance of common stock, Series A non-voting convertible preferred stock, and pre-funded warrants in connection with the 2024 PIPE Financing |  |  | $ 56,097 | $ 6 | 144,433 |  |  | 144,439
Issuance of common stock, Series A non-voting convertible preferred stock, and pre-funded warrants in connection with the 2024 PIPE Financing (in Shares) |  |  | 2,439 | 5,600,000 |  |  |  |
Issuance cost of the 2024 PIPE Financing |  |  | $ (3,256) |  | (8,573) |  |  | (8,573)
Stock-based compensation expense |  |  |  |  | 1,750 |  |  | 1,750
Net loss |  |  |  |  |  |  | (28,623) | (28,623)
Balance at Sep. 30, 2024 | $ 2,931 |  | $ 52,841 | $ 35 | 397,345 |  | (57,943) | 342,368
Balance (in Shares) at Sep. 30, 2024 | 137,138 |  | 2,439 | 34,998,550 |  |  |  |
Balance at Dec. 31, 2024 | $ 2,931 |  |  | $ 37 | 463,018 | $ (41) | (83,724) | 382,221
Balance (in Shares) at Dec. 31, 2024 | 137,138 |  |  | 37,440,510 |  |  |  |
Stock-based compensation expense |  |  |  |  | 3,468 |  |  | 3,468
Net change in unrealized gains (losses) on marketable securities |  |  |  |  |  | 35 |  | 35
Net loss |  |  |  |  |  |  | (20,999) | (20,999)
Balance at Mar. 31, 2025 | $ 2,931 |  |  | $ 37 | 466,486 | (6) | (104,723) | 364,725
Balance (in Shares) at Mar. 31, 2025 | 137,138 |  |  | 37,440,510 |  |  |  |
Balance at Dec. 31, 2024 | $ 2,931 |  |  | $ 37 | 463,018 | (41) | (83,724) | 382,221
Balance (in Shares) at Dec. 31, 2024 | 137,138 |  |  | 37,440,510 |  |  |  |
Balance at Sep. 30, 2025 | $ 2,931 |  |  | $ 48 | 643,201 | 185 | (159,574) | 486,791
Balance (in Shares) at Sep. 30, 2025 | 137,138 |  |  | 48,384,150 |  |  |  |
Balance at Mar. 31, 2025 | $ 2,931 |  |  | $ 37 | 466,486 | (6) | (104,723) | 364,725
Balance (in Shares) at Mar. 31, 2025 | 137,138 |  |  | 37,440,510 |  |  |  |
Issuance of common stock under employee stock purchase plan |  |  |  |  | 109 |  |  | 109
Issuance of common stock under employee stock purchase plan (in Shares) |  |  |  | 10,235 |  |  |  |
Stock-based compensation expense |  |  |  |  | 3,403 |  |  | 3,403
Net change in unrealized gains (losses) on marketable securities |  |  |  |  |  | (21) |  | (21)
Net loss |  |  |  |  |  |  | (24,574) | (24,574)
Balance at Jun. 30, 2025 | $ 2,931 |  |  | $ 37 | 469,998 | (27) | (129,297) | 343,642
Balance (in Shares) at Jun. 30, 2025 | 137,138 |  |  | 37,450,745 |  |  |  |
Issuance of common stock and pre-funded warrants in connection with the 2025 PIPE Financing |  |  |  | $ 11 | 179,989 |  |  | 180,000
Issuance of common stock and pre-funded warrants in connection with the 2025 PIPE Financing (in Shares) |  |  |  | 10,933,405 |  |  |  |
Issuance cost of the 2025 PIPE Financing |  |  |  |  | (10,356) |  |  | (10,356)
Stock-based compensation expense |  |  |  |  | 3,570 |  |  | 3,570
Net change in unrealized gains (losses) on marketable securities |  |  |  |  |  | 212 |  | 212
Net loss |  |  |  |  |  |  | (30,277) | (30,277)
Balance at Sep. 30, 2025 | $ 2,931 |  |  | $ 48 | $ 643,201 | $ 185 | $ (159,574) | $ 486,791
Balance (in Shares) at Sep. 30, 2025 | 137,138 |  |  | 48,384,150 |  |  |  |

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