<SEC-DOCUMENT>0001415889-25-005908-index.html : 20250227
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<ACCEPTANCE-DATETIME>20250227184249
ACCESSION NUMBER:		0001415889-25-005908
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20250210
FILED AS OF DATE:		20250227
DATE AS OF CHANGE:		20250227

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Venrock Healthcare Capital Partners III, L.P.
		CENTRAL INDEX KEY:			0001738048
		ORGANIZATION NAME:           	
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22873
		FILM NUMBER:		25681627

	BUSINESS ADDRESS:	
		STREET 1:		530 FIFTH AVENUE, 22ND FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10036
		BUSINESS PHONE:		212-444-4100

	MAIL ADDRESS:	
		STREET 1:		530 FIFTH AVENUE, 22ND FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10036

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Koh Bong Y
		CENTRAL INDEX KEY:			0001615979
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22873
		FILM NUMBER:		25681622

	MAIL ADDRESS:	
		STREET 1:		7 BRYANT PARK
		STREET 2:		23RD FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10018

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Shah Nimish P
		CENTRAL INDEX KEY:			0001698082
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22873
		FILM NUMBER:		25681621

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		650-475-3734

	MAIL ADDRESS:	
		STREET 1:		7 BRYANT PARK
		STREET 2:		23RD FLOOR
		CITY:			NEW YORK CITY
		STATE:			NY
		ZIP:			10018

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			VHCP Management EG, LLC
		CENTRAL INDEX KEY:			0001808518
		ORGANIZATION NAME:           	
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22873
		FILM NUMBER:		25681625

	BUSINESS ADDRESS:	
		STREET 1:		3340 HILLVIEW AVENUE
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304
		BUSINESS PHONE:		6505619580

	MAIL ADDRESS:	
		STREET 1:		3340 HILLVIEW AVENUE
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			VHCP Management III, LLC
		CENTRAL INDEX KEY:			0001738053
		ORGANIZATION NAME:           	
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22873
		FILM NUMBER:		25681623

	BUSINESS ADDRESS:	
		STREET 1:		7 BRYANT PARK
		STREET 2:		23RD FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10018
		BUSINESS PHONE:		(650) 561-9580

	MAIL ADDRESS:	
		STREET 1:		7 BRYANT PARK
		STREET 2:		23RD FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10018

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			VHCP Co-Investment Holdings III, LLC
		CENTRAL INDEX KEY:			0001750761
		ORGANIZATION NAME:           	
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22873
		FILM NUMBER:		25681626

	BUSINESS ADDRESS:	
		STREET 1:		7 BRYANT PARK
		STREET 2:		23RD FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10018
		BUSINESS PHONE:		650-475-3734

	MAIL ADDRESS:	
		STREET 1:		7 BRYANT PARK
		STREET 2:		23RD FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10018

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Venrock Healthcare Capital Partners EG, L.P.
		CENTRAL INDEX KEY:			0001808512
		ORGANIZATION NAME:           	
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22873
		FILM NUMBER:		25681624

	BUSINESS ADDRESS:	
		STREET 1:		3340 HILLVIEW AVENUE
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304
		BUSINESS PHONE:		6505619580

	MAIL ADDRESS:	
		STREET 1:		3340 HILLVIEW AVENUE
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94304

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Oruka Therapeutics, Inc.
		CENTRAL INDEX KEY:			0000907654
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				363855489
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		855 OAK GROVE AVE.
		STREET 2:		SUITE 100
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025
		BUSINESS PHONE:		650-606-7910

	MAIL ADDRESS:	
		STREET 1:		855 OAK GROVE AVE.
		STREET 2:		SUITE 100
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ARCA biopharma, Inc.
		DATE OF NAME CHANGE:	20090128

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NUVELO INC
		DATE OF NAME CHANGE:	20030203

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	HYSEQ INC
		DATE OF NAME CHANGE:	19970610
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