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Expenses by nature (Details) - USD ($) | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2024 | Sep. 30, 2023 | Sep. 30, 2024 | Sep. 30, 2023
Research and development [Abstract] |  |  |  |  |
External research and development expenses |  | $ 6,728,000 | $ 5,207,000 | $ 21,651,000 | $ 16,521,000
Employee expenses | [1],[2] | 1,606,000 | 1,812,000 | 4,964,000 | 4,857,000
Depreciation |  | 5,000 | 8,000 | 16,000 | 28,000
Other expenses |  | 58,000 | 61,000 | 179,000 | 164,000
Total research and development expenses |  | 8,397,000 | 7,088,000 | 26,810,000 | 21,570,000
General and administrative [Abstract] |  |  |  |  |
External costs |  | 3,016,000 | 1,725,000 | 7,253,000 | 5,834,000
Employee expenses | [2],[3] | 1,134,000 | 834,000 | 3,084,000 | 2,450,000
Depreciation |  | 74,000 | 72,000 | 221,000 | 209,000
Total general and administrative expenses |  | 4,224,000 | 2,631,000 | 10,558,000 | 8,493,000
Total operating expenses |  | 12,621,000 | 9,719,000 | 37,368,000 | 30,063,000
Share based compensation expense (benefit) included in employees expenses for employees in research and development department |  | 100,000 | 400,000 | 200,000 | 1,000,000
Share-based compensation expense (benefit) included in employees expenses for employees in general and administrative department |  | 100 | 200,000 | 200,000 | 700,000
Foreign exchange gain/loss [Abstract] |  |  |  |  |
Foreign exchange gain/(loss) |  | $ (1,845,000) | $ 1,833,000 | (58,000) | $ 232,000
Loss before tax higher/lower related to translation of cash held |  |  |  | $ 3,400,000 |
[1] | Included in employee expenses is a share based compensation expense of $0.1 million and $0.2 million for the three and nine months ended September 30, 2024, respectively, relating to employees in the research and development department (three and nine months ended September 30, 2023, $0.4 million and $1.0 million, respectively).
[2] | Includes termination expenses incurred in the nine months ended September 30, 2024.
[3] | Included in employee expenses is share based compensation expense of $0.1 million and $0.2 million for the three and nine months ended September 30, 2024, respectively, relating to employees in the general and administrative department (three and nine months ended September 30, 2023, $0.2 million and $0.7 million, respectively).

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