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Expenses by nature (Details) - USD ($)
 3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Research and development [Abstract]        
External research and development expenses $ 6,728,000 $ 5,207,000 $ 21,651,000 $ 16,521,000
Employee expenses [1],[2] 1,606,000 1,812,000 4,964,000 4,857,000
Depreciation 5,000 8,000 16,000 28,000
Other expenses 58,000 61,000 179,000 164,000
Total research and development expenses 8,397,000 7,088,000 26,810,000 21,570,000
General and administrative [Abstract]        
External costs 3,016,000 1,725,000 7,253,000 5,834,000
Employee expenses [2],[3] 1,134,000 834,000 3,084,000 2,450,000
Depreciation 74,000 72,000 221,000 209,000
Total general and administrative expenses 4,224,000 2,631,000 10,558,000 8,493,000
Total operating expenses 12,621,000 9,719,000 37,368,000 30,063,000
Share based compensation expense (benefit) included in employees expenses for employees in research and development department 100,000 400,000 200,000 1,000,000
Share-based compensation expense (benefit) included in employees expenses for employees in general and administrative department 100 200,000 200,000 700,000
Foreign exchange gain/loss [Abstract]        
Foreign exchange gain/(loss) $ (1,845,000) $ 1,833,000 (58,000) $ 232,000
Loss before tax higher/lower related to translation of cash held     $ 3,400,000  
[1] Included in employee expenses is a share based compensation expense of $0.1 million and $0.2 million for the three and nine months ended September 30, 2024, respectively, relating to employees in the research and development department (three and nine months ended September 30, 2023, $0.4 million and $1.0 million, respectively).
[2] Includes termination expenses incurred in the nine months ended September 30, 2024.
[3] Included in employee expenses is share based compensation expense of $0.1 million and $0.2 million for the three and nine months ended September 30, 2024, respectively, relating to employees in the general and administrative department (three and nine months ended September 30, 2023, $0.2 million and $0.7 million, respectively).