<SEC-DOCUMENT>0000902664-25-000810.txt : 20250210
<SEC-HEADER>0000902664-25-000810.hdr.sgml : 20250210
<ACCEPTANCE-DATETIME>20250210172958
ACCESSION NUMBER:		0000902664-25-000810
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20250210
DATE AS OF CHANGE:		20250210

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			GH Research PLC
		CENTRAL INDEX KEY:			0001855129
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			L2
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-92661
		FILM NUMBER:		25606810

	BUSINESS ADDRESS:	
		STREET 1:		JOSHUA DAWSON HOUSE
		STREET 2:		DAWSON STREET
		CITY:			DUBLIN 2
		STATE:			L2
		ZIP:			D02 RY95
		BUSINESS PHONE:		353 1 437 8334

	MAIL ADDRESS:	
		STREET 1:		JOSHUA DAWSON HOUSE
		STREET 2:		DAWSON STREET
		CITY:			DUBLIN 2
		STATE:			L2
		ZIP:			D02 RY95

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Lynx1 Capital Management LP
		CENTRAL INDEX KEY:			0001910456
		ORGANIZATION NAME:           	
		IRS NUMBER:				851134656
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		151 CALLE DE SAN FRANCISCO
		STREET 2:		SUITE 200 PMB 1237
		CITY:			SAN JUAN
		STATE:			PR
		ZIP:			00901-1607
		BUSINESS PHONE:		703-963-7214

	MAIL ADDRESS:	
		STREET 1:		151 CALLE DE SAN FRANCISCO
		STREET 2:		SUITE 200 PMB 1237
		CITY:			SAN JUAN
		STATE:			PR
		ZIP:			00901-1607
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <previousAccessionNumber>0000902664-24-001825</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <!-- Field: Pseudo-Tag; ID: Name; Data: Lynx1 Capital Management LP -->
          <cik>0001910456</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>3</amendmentNo>
      <securitiesClassTitle>Ordinary shares, nominal value $0.025 per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>02/06/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001855129</issuerCik>
        <issuerName>GH Research PLC</issuerName>
        <issuerCusip>G3855L106</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>Joshua Dawson House</com:street1>
          <com:street2>Dawson Street</com:street2>
          <com:city>Dublin 2</com:city>
          <com:stateOrCountry>L2</com:stateOrCountry>
          <com:zipCode>RY95</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Lynx1 Capital Management LP</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>6353069.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>6353069.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>6353069.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>10.2</classPercent>
      <typeOfReportingPerson>PN</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Weston Nichols</reportingPersonName>
      <citizenshipOrOrganization>X1</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>6353069.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>6353069.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>6353069.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>10.2</classPercent>
      <typeOfReportingPerson>IN</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>GH Research PLC</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>Joshua Dawson House, Dawson Street, Dublin 2 L2, D02 RY95</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>(i)  Lynx1 Capital Management LP (the "Investment Manager"), a Delaware limited partnership, and the investment manager to Lynx1 Master Fund LP (the "Lynx1 Fund") and a managed account, with respect to the ordinary shares, nominal value $0.025 per share ("Ordinary Shares") of GH Research PLC, an Irish public limited company (the "Company") directly held by the Lynx1 Fund and the managed account; and

(ii)  Mr. Weston Nichols ("Mr. Nichols"), the sole member of Lynx1 Capital Management GP LLC, the general partner of the Investment Manager, with respect to the Ordinary Shares directly held by the Lynx1 Fund and the managed account.

The foregoing persons are hereinafter sometimes collectively referred to as the "Reporting Persons."

The filing of this statement should not be construed as an admission that any of the foregoing persons or any Reporting Person is, for the purposes of Section 13 of the Act, the beneficial owner of the securities reported herein.</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>Lynx1 Capital Management LP
151 Calle de San Francisco
Suite 200, PMB 1237
San Juan, PR 00901-1607

Weston Nichols
c/o Lynx1 Capital Management LP
151 Calle de San Francisco
Suite 200, PMB 1237
San Juan, PR 00901-1607</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Investment Manager - Delaware
Mr. Nichols - United States of America</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>The information required by Item 4(a) is set forth in Row 9 of the cover page for each of the Reporting Persons and is incorporated herein by reference.

The percentage set forth in this Schedule 13G is calculated based upon an aggregate of 62,028,145 Ordinary Shares, after giving the effect to the completion of the underwritten public offering, as described in the Company's Prospectus Supplement filed pursuant to Rule 424(b)(5) with the Securities and Exchange Commission on February 5, 2025 and the Company's Report of Foreign Issuer on Form 6-K filed with the Securities and Exchange Commission on February 6, 2025, all as described therein.</amountBeneficiallyOwned>
        <classPercent>10.2%</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>The information required by Item 4(c)(i) is set forth in Row 5 of the cover page for each of the Reporting Persons and is incorporated herein by reference.</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>The information required by Item 4(c)(ii) is set forth in Row 6 of the cover page for each of the Reporting Persons and is incorporated herein by reference.</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>The information required by Item 4(c)(iii) is set forth in Row 7 of the cover page for each of the Reporting Persons and is incorporated herein by reference.</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>The information required by Item 4(c)(iv) is set forth in Row 8 of the cover page for each of the Reporting Persons and is incorporated herein by reference.</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
      </item5>
      <item6>
        <notApplicableFlag>N</notApplicableFlag>
        <ownershipMoreThan5PercentOnBehalfOfAnotherPerson>The Lynx1 Fund has the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, the Ordinary Shares reported herein.</ownershipMoreThan5PercentOnBehalfOfAnotherPerson>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>Lynx1 Capital Management LP</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Weston Nichols</signature>
        <title>By: Lynx1 Capital Management GP LLC, General Partner, By: Weston Nichols, Sole Member</title>
        <date>02/10/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Weston Nichols</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Weston Nichols</signature>
        <title>Weston Nichols, Individually</title>
        <date>02/10/2025</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
