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Share-Based Compensation - Additional Information (Details) |  |  |  |  | 1 Months Ended | 3 Months Ended | 9 Months Ended |
--- | --- | --- | --- | --- | --- | --- | --- | ---
Jun. 08, 2020 shares | Jan. 03, 2019 USD ($) $ / shares shares | Oct. 12, 2018 shares | Jan. 01, 2018 shares | Jun. 30, 2020 USD ($) $ / shares shares | Dec. 31, 2019 USD ($) | Jun. 30, 2019 USD ($) $ / shares shares | Mar. 31, 2017 shares | Sep. 30, 2020 USD ($) | Sep. 30, 2019 USD ($) | Sep. 30, 2020 USD ($) shares | Sep. 30, 2019 USD ($) | May 31, 2019 shares
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Share-based compensation expense | $ |  |  |  |  |  |  |  |  | $ 6,763,000 | $ 7,243,000 | $ 21,499,000 | $ 21,902,000 |
Unrecognized compensation cost of options and RSUs | $ |  |  |  |  |  |  |  |  | $ 34,300,000 |  | $ 34,300,000 |  |
Expected to be recognized over a weighted average period |  |  |  |  |  |  |  |  |  |  | 1 year 8 months 1 day |  |
Options | General and Administrative Expenses |  |  |  |  |  |  |  |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Share-based compensation expense | $ |  |  |  |  |  | $ 900,000 |  |  |  |  |  |  |
Options | Elizabeth Barrett |  |  |  |  |  |  |  |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Option to purchase of ordinary shares |  | 277,432 |  |  |  |  |  |  |  |  |  |  |
Exercise price of option to purchase of ordinary shares | $ / shares |  | $ 47.57 |  |  |  |  |  |  |  |  |  |  |
Options | Non-employee Directors |  |  |  |  |  |  |  |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Options granted, expected term |  |  |  |  | 10 years |  | 10 years |  |  |  |  |  |
Awards vesting period |  |  |  |  | 1 year |  | 1 year |  |  |  |  |  |
Number of stock options approved for grants |  |  |  |  | 70,000 |  | 70,000 |  |  |  |  |  |
Stock options granted |  |  |  |  | 10,000 |  | 10,000 |  |  |  |  |  |
Exercise of option to ordinary shares conversion ratio |  |  |  |  | 1 |  | 1 |  |  |  |  |  |
Stock option exercise | $ / shares |  |  |  |  | $ 28.24 |  | $ 34.83 |  |  |  |  |  |
Estimated fair value of options granted | $ |  |  |  |  | $ 1,500,000 |  | $ 1,900,000 |  |  |  |  |  |
Options | Chairman of Board of Directors |  |  |  |  |  |  |  |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Stock options granted |  |  |  |  | 10,000 |  | 10,000 |  |  |  |  |  |
Options | Tranche One |  |  |  |  |  |  |  |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Vesting percentage |  |  |  |  |  |  |  |  |  |  | 33.00% |  |
Restricted Stock Units (RSUs) |  |  |  |  |  |  |  |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Awards vesting period |  |  |  |  |  |  |  |  |  |  | 2 years |  |
Share-based compensation expense | $ |  |  |  |  |  | $ 0 |  |  |  |  |  |  |
Restricted Stock Units (RSUs) | Elizabeth Barrett |  |  |  |  |  |  |  |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Option to purchase of ordinary shares |  | 317,065 |  |  |  |  |  |  |  |  |  |  |
Restricted Stock Units (RSUs) | Tranche One |  |  |  |  |  |  |  |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Vesting percentage |  |  |  |  |  |  |  |  |  |  | 33.00% |  |
2017 Equity Incentive Plan |  |  |  |  |  |  |  |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Maximum number of ordinary share issuable under the 2017 incentive plan |  |  |  |  |  |  |  | 1,400,000 |  |  | 5,600,000 |  |
Number of ordinary shares reserved for issuance, percentage |  |  |  |  |  |  |  |  |  |  | 12.00% |  |
Increase in number of ordinary share issuable under the 2017 incentive plan | 400,000 |  | 1,900,000 | 250,167 |  |  |  |  |  |  |  |  |
Stock Options and Restricted Stock Units (RSUs) | Elizabeth Barrett |  |  |  |  |  |  |  |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Fair value | $ |  | $ 24,100,000 |  |  |  |  |  |  |  |  |  |  |
Plan | Options |  |  |  |  |  |  |  |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Awards vesting period |  |  |  |  |  |  |  |  |  |  | 3 years |  |
Combined voting power percentage |  |  |  |  |  |  |  |  |  |  | 10.00% |  |
Ordinary Shares | 2019 Inducement Plan |  |  |  |  |  |  |  |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Number of stock options approved for grants |  |  |  |  |  |  |  |  |  |  |  |  | 900,000
Ordinary Shares | 2017 Equity Incentive Plan |  |  |  |  |  |  |  |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Maximum number of ordinary share issuable under the 2017 incentive plan | 3,950,167 |  | 3,550,167 | 1,650,167 |  |  |  |  |  |  |  |  |
Maximum | Plan | Options |  |  |  |  |  |  |  |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Options granted, expected term |  |  |  |  |  |  |  |  |  |  | 10 years |  |
Minimum | Plan | Options |  |  |  |  |  |  |  |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise price of stock options as percentage of fair market value of shares on grant date |  |  |  |  |  |  |  |  |  |  | 100.00% |  |
Stock options exercise price percentage for individuals possesses more than 10% of the combined voter power |  |  |  |  |  |  |  |  |  |  | 110.00% |  |

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