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Significant Accounting Policies - Additional Information (Detail)
1 Months Ended 12 Months Ended
Jul. 31, 2020
shares
Nov. 30, 2015
Dec. 31, 2020
USD ($)
Segment
Agreement
Dec. 31, 2019
USD ($)
Significant Accounting Policies [Line Items]        
Number of operating segments | Segment     1  
Maturity days for highly liquid investments     The Company considers all short-term, highly liquid investments with original maturities of 90 days or less at acquisition date to be cash equivalents.  
Restricted cash     $ 878,000 $ 878,000
Operating lease option to extent     true  
Operating lease option to terminate   true true  
Impairment loss of long lived assets     $ 0 0
Conversion of convertible preferred stock into common stock upon initial public offering, shares | shares 61,992,534      
Description of Income tax benefit, likelihood of realized upon ultimate settlement     greater than 50%  
Laboratory and Computer Equipment [Member]        
Significant Accounting Policies [Line Items]        
Property and equipment, useful life     3 years  
Furniture and Fixtures [Member]        
Significant Accounting Policies [Line Items]        
Property and equipment, useful life     5 years  
Genentech [Member] | Genentech Agreement [Member]        
Significant Accounting Policies [Line Items]        
Number of collaboration and license agreement | Agreement     1  
Collaboration and license agreement entered date     Dec. 11, 2020  
Letter of Credit [Member]        
Significant Accounting Policies [Line Items]        
Restricted cash     $ 878,000 $ 878,000